Rapid determination of neomycin in biological samples using fluorescent sensor based on quantum dots with doubly selective binding sites

Wan, Yingchun; Liu, Yanjie; Liu, Chen; Ma, Huiting; Yu, Hao; Kang, Jia-wei; Gao, Chen-long; Wu, Zhong-qiao; Zheng, Dan; Lü, Bin

doi:10.1016/j.jpba.2018.02.028

Cited by 27 publications

(16 citation statements)

References 28 publications

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“…MIPs are polymers processed using molecularly imprinted techniques that leave cavities in the polymer matrix and have an affinity for the template molecules. For the FL sensing of AGs, FL-emitting nanomaterials such as QDs [29][30][31] and FL-emitting metal-organic framework (MOF) NPs [32] have been employed as supports to construct MIPs. Typically, He and Du's group fabricated a MIP-coated europium metal-organic framework by using 4-vinylpyridine as the main monomer, ethylene glycol dimethacrylate as the cross-linking monomer, and lincomycin as the template.…”

Section: Turn-off Fluorescent Analysis Strategiesmentioning

confidence: 99%

“…The LOD for lincomycin was calculated to be 16.2 nM [32]. In addition, dual recognition MIPs have been constructed for highly specific sensing of AGs [29,30]. For example, a dual-recognition MIP was constructed for the highly specific sensing of kanamycin by using CdSe QDs as supports, methacrylic acid, and thiol-modified aptamers as functional monomers.…”

Section: Turn-off Fluorescent Analysis Strategiesmentioning

confidence: 99%

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Recent Advances in Optical Detection of Aminoglycosides

Zhou

Cao

2020

Applied Sciences

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Aminoglycosides (AGs) are broad-spectrum antibiotics used in both human infection and animal medicine. The overuse of AGs causes undesirable residues in food, leading to serious health problems due to food chain accumulation. In recent years, various methods have been developed to determine AGs in food. Among these methods, fluorescent (FL), colorimetric and chemiluminescent (CL) optical methods possess advantages such as their simple instrumentation, low cost, simple operation, feasibility of realizing visualization, and smartphone imaging. This mini-review summarizes optical assays for the detection of AGs in food developed in recent years. The detection principles for different categories are discussed. Then, the amplification techniques for the ultrasensitive detection of AGs are introduced. We also discuss multiplex methods for the simultaneous detection of AGs. Finally, the challenges and future prospects are discussed in the Conclusions and Perspectives section.

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Section: Turn-off Fluorescent Analysis Strategiesmentioning

confidence: 99%

Section: Turn-off Fluorescent Analysis Strategiesmentioning

confidence: 99%

Recent Advances in Optical Detection of Aminoglycosides

Zhou

Cao

2020

Applied Sciences

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“…To address this problem, combining sample pretreatment with the detection process could be an alternative choice. To determine neomycin in pork, swine liver and kidney, fish meat and liver, chicken meat and kidney, and milk samples, the samples were firstly pre-treated by liquid-liquid extraction and solidphase extraction to isolate and concentrate neomycin, and then subjected to the MIFN sensor and HPLC-FLD analysis, respectively [63] . The results indicated that both the sensitivity and selectivity of the MIFN sensor were higher than those of HPLC-FLD.…”

Section: Detection Of the Veterinary Drugs Residuesmentioning

confidence: 99%

The Recent Advances of Fluorescent Sensors Based on Molecularly Imprinted Fluorescent Nanoparticles for Pharmaceutical Analysis

Wang

Pan

et al. 2020

CURR MED SCI

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Summary Fluorescent nanoparticles have good chemical stability and photostability, controllable optical properties and larger stokes shift. In light of their designability and functionability, the fluorescent nanoparticles are widely used as the fluorescent probes for diverse applications. To enhance the sensitivity and selectivity, the combination of the fluorescent nanoparticles with the molecularly imprinted polymer, i.e. molecularly imprinted fluorescent nanoparticles (MIFN), was an effective way. The sensor based on MIFN (the MIFN sensor) could be more compatible with the complex sample matrix, which was especially widely adopted in medical and biological analysis. In this mini-review, the construction method, detective mechanism and types of MIFN sensors are elaborated. The current applications of MIFN sensors in pharmaceutical analysis, including pesticides/herbicide, veterinary drugs/drugs residues and human related proteins, are highlighted based on the literature in the recent three years. Finally, the research prospect and development trend of the MIFN sensor are forecasted.

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“…As detailed in other sections, it is common to add components to MIP that improve selective recognition, usually by double recognition. Wan et al [128] developed a fluorescent sensor based on CdTe QDs with doubly selective binding sites for determination of neomycin. The QDs were encapsulated in SiO 2 and then a silica-based MIP was fabricated using a silane boronate monomer, that covalently recognizes the analyte, while the rest of the monomers allowed non-covalent recognition.…”

Section: Three-dimensional Compositesmentioning

confidence: 99%

Molecularly Imprinted Polymer-Based Hybrid Materials for the Development of Optical Sensors

Rico-Yuste¹,

Carrasco

2019

Polymers

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We report on the development of new optical sensors using molecularly imprinted polymers (MIPs) combined with different materials and explore the novel strategies followed in order to overcome some of the limitations found during the last decade in terms of performance. This review pretends to offer a general overview, mainly focused on the last 3 years, on how the new fabrication procedures enable the synthesis of hybrid materials enhancing not only the recognition ability of the polymer but the optical signal. Introduction describes MIPs as biomimetic recognition elements, their properties and applications, emphasizing on each step of the fabrication/recognition procedure. The state of the art is presented and the change in the publication trend between electrochemical and optical sensor devices is thoroughly discussed according to the new fabrication and micro/nano-structuring techniques paving the way for a new generation of MIP-based optical sensors. We want to offer the reader a different perspective based on the materials science in contrast to other overviews. Different substrates for anchoring MIPs are considered and distributed in different sections according to the dimensionality and the nature of the composite, highlighting the synergetic effect obtained as a result of merging both materials to achieve the final goal.

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Rapid determination of neomycin in biological samples using fluorescent sensor based on quantum dots with doubly selective binding sites

Cited by 27 publications

References 28 publications

Recent Advances in Optical Detection of Aminoglycosides

Recent Advances in Optical Detection of Aminoglycosides

The Recent Advances of Fluorescent Sensors Based on Molecularly Imprinted Fluorescent Nanoparticles for Pharmaceutical Analysis

Molecularly Imprinted Polymer-Based Hybrid Materials for the Development of Optical Sensors

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