Rapid determination of dopamine in human plasma using a gold nanoparticle-based dual-mode sensing system

Zhang, Yali; Qi, Suijian; Liu, Zhonggang; Shi, Yupeng; Yue, Wanqing; Yi, Changqing

doi:10.1016/j.msec.2015.12.038

Cited by 64 publications

(30 citation statements)

References 53 publications

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“…A DNA aptamer for dopamine was obtained by directly converting the RNA aptamer. [94] A few studies used this DNA dopamine aptamer to perform the label-free detection, [95,96] although the binding property of this aptamer was questioned. [97] In 2018, a new DNA aptamer for dopamine was selected by Stojanović and co-workers ( Figure 6A).…”

Section: Dopamine Melamine and Kanamycinmentioning

confidence: 99%

Label‐Free Colorimetric Biosensors Based on Aptamers and Gold Nanoparticles: A Critical Review

Zhang

Liu

2020

Analysis & Sensing

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Taking advantage of the adsorption of single‐stranded DNA oligonucleotides by gold nanoparticles (AuNPs) and the protection effect of the adsorbed DNA against salt‐induced aggregation of AuNPs, a label‐free colorimetric sensor for the detection of DNA was reported in 2004. Since then, the range of target molecules has extended from complementary nucleic acids to metal ions and small molecules by using aptamers. In the presence of target molecules, a blue color arising from aggregated AuNPs is expected. However, these sensors only considered aptamer binding to its target, and the adsorption of aptamers by AuNPs, while the target/AuNP interactions were ignored. We recently found that target adsorption can often dominate the system. In this Review, we list literature examples of using this label‐free strategy for sensing aptamer targets. Seven target analytes are discussed in detail. For As(III), dopamine, melamine, kanamycin, adenosine, and ATP, target adsorption dominated, and the same color change was observed even with non‐aptamer sequences. Only in the case of K+ detection, did the effect of specific aptamer binding dominate, attributable to weak K+/AuNP interactions. These examples call for a careful evaluation of target adsorption and the use of non‐aptamer control sequences in validating these sensors.

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Section: Dopamine Melamine and Kanamycinmentioning

confidence: 99%

Label‐Free Colorimetric Biosensors Based on Aptamers and Gold Nanoparticles: A Critical Review

Zhang

Liu

2020

Analysis & Sensing

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“…The aggregation of several NPs based on interactions other than hydrogen bonding was employed for colorimetric detection of DA [303,304]. As previously mentioned, AgNPs have also been used for the colorimetric sensing of DA.…”

Section: Optical Sensorsmentioning

confidence: 99%

Recent Advances in Electrochemical and Optical Sensing of Dopamine

Eddin

Fen

2020

Sensors

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Nowadays, several neurological disorders and neurocrine tumours are associated with dopamine (DA) concentrations in various biological fluids. Highly accurate and ultrasensitive detection of DA levels in different biological samples in real-time can change and improve the quality of a patient’s life in addition to reducing the treatment cost. Therefore, the design and development of diagnostic tool for in vivo and in vitro monitoring of DA is of considerable clinical and pharmacological importance. In recent decades, a large number of techniques have been established for DA detection, including chromatography coupled to mass spectrometry, spectroscopic approaches, and electrochemical (EC) methods. These methods are effective, but most of them still have some drawbacks such as consuming time, effort, and money. Added to that, sometimes they need complex procedures to obtain good sensitivity and suffer from low selectivity due to interference from other biological species such as uric acid (UA) and ascorbic acid (AA). Advanced materials can offer remarkable opportunities to overcome drawbacks in conventional DA sensors. This review aims to explain challenges related to DA detection using different techniques, and to summarize and highlight recent advancements in materials used and approaches applied for several sensor surface modification for the monitoring of DA. Also, it focuses on the analytical features of the EC and optical-based sensing techniques available.

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“…Good linearity was obtained over a range of 5.0 × 10 -8 -5.0 × 10 -5 M and the detection limit was estimated to be 2.5 nM (3σ) which is better than the limit of the recently reported probes. [27][28][29][30] The method has better selectivity than other reported AuNP-based colorimetric methods for detecting DA. 14,19,31,32…”

Section: Detection Of Da Under Optimal Phmentioning

confidence: 90%

Un-functionalized Gold Nanoparticles as a Simple Colorimetric Probe for Sensitive and Selective Detection of Dopamine

Khanyile¹,

Krause²,

Vilakazi³

et al. 2019

S.Afr.j.chem.

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A dopamine (DA) colorimetric probe based on the growth and aggregation of un-functionalized gold nanoparticles (AuNPs) is reported. Upon addition of AuNPs to dopamine at various concentrations, the shape, size and colour change of the nanoparticles results in spectral shifts to higher wavelengths and hence colour change is the mode of detection. The colour change can be easily observed by the naked eye from as low as 5.0 nM DA, even under sub-optimal conditions. Under optimal pH conditions the calculated limit of detection was 2.5 nM (3ó). The probe was successfully applied to whole blood sample and showed good selectivity and sensitivity towards DA. The simple, sensitive and selective probe could be an excellent alternative for on-site and immediate detection of DA without the use of instrumentation and would thus be useful for rapid diagnostic applications.

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Rapid determination of dopamine in human plasma using a gold nanoparticle-based dual-mode sensing system

Cited by 64 publications

References 53 publications

Label‐Free Colorimetric Biosensors Based on Aptamers and Gold Nanoparticles: A Critical Review

Label‐Free Colorimetric Biosensors Based on Aptamers and Gold Nanoparticles: A Critical Review

Recent Advances in Electrochemical and Optical Sensing of Dopamine

Un-functionalized Gold Nanoparticles as a Simple Colorimetric Probe for Sensitive and Selective Detection of Dopamine

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