Rapid degradation of ferulic acid via 4-vinylguaiacol and vanillin by a newly isolated strain of Bacillus coagulans

Obtenção de vanilina: oportunidade biotecnológica

“…Neste caso a biotransformação foi testada como a linhagem de Bacillus coagulans BK07, a qual mostrou uma rápida descarboxilação de ácido ferúlico em 4-vinilguaiacol, o qual foi imediatamente convertido em vanilina e oxidado para ácido vanílico. O ácido vanílico foi, então, desmetilado e obteve-se ácido protocatecóico 43 . O microrganismo Streptomyces setonii, através do metabolismo do ácido ferúlico, é capaz de produzir vanilina e ácido protocatecóico 44 .…”

Phenolic Acid-Mediated Regulation of the padC Gene, Encoding the Phenolic Acid Decarboxylase of Bacillus subtilis

“…Some of these phenolic acids have toxic properties, while others may provide a potential carbon source (16). Therefore, B. subtilis has evolved a mechanism that allows it to respond quickly to phenolic acid fluctuations, while this is less critical for bacteria such as B. pumilus or lactic acid bacteria, which are commensal or colonize nutrient-rich and "bacterium-friendly" habitats (12).…”

Formation of 4-Vinyl Guaiacol as an Intermediate in Bioconversion of Ferulic Acid bySchizophyllum commune

“…In previous reports, ferulic acid was converted into 4-vinyl guaiacol by certain microorganisms, [13][14][15][16][17][18] but 4-vinyl guaiacol was not identified in the products metabolized by whiterot basidiomycetes Pycnoporus cinnabarinus 6) or Sporotrichum pulverulentum (syn. Phanerochaete chrysosporium), 19) or by mycorrhizal basidiomycetes Laccaria spp.…”