Changes in longitudinal relaxation time (T 1 ) and proton density (PD) are sensitive indicators of microstructural alterations associated with various central nervous system diseases as well as brain maturation and aging. In this work, we introduce a new approach for rapid and accurate highresolution (HR) or ultra HR (UHR) mapping of T 1 and apparent PD (APD) of the brain with correction of radiofrequency field, B 1 , inhomogeneities. The four-angle method (FAM) uses four spoiled-gradient recalled-echo (SPGR) images acquired at different flip angles (FA) and short repetition times (TRs). The first two SPGR images are acquired at low-spatial resolution and used to accurately map the active B 1 + field with the recently introduced steady-state double angle method (SS-DAM). The estimated B 1 + map is used in conjunction with the two other SPGR images, acquired at HR or UHR, to map T 1 and APD. The method is evaluated with numerical, phantom, and in-vivo imaging measurements. Furthermore, we investigated imaging acceleration methods to further shorten the acquisition time. Our results indicate that FAM provides an accurate method for simultaneous HR or UHR mapping of T 1 and APD in human brain in clinical highfield MRI. Derived parameter maps without B 1 + correction suffer from large inaccuracies, but that this issue is well-corrected through use of the SS-DAM. Furthermore, the use of the SPGR imaging, with short TR and phased-array coil acquisition permits substantial imaging acceleration and enables robust HR or UHR T 1 and APD mapping in a clinically acceptable time frame with whole brain coverage obtained in less than 2 min or 5 min. The method exhibits high reproducibility and benefits from the use of the conventional SPGR sequence, available in all