Rapid and sensitive strategy for Human Papillomavirus (HPV) detection using a gene-based DNA nanobiosensor

Azizah, N.; Hashim, U.; Nadzirah, Sh.; Ruslinda, A. Rahim

doi:10.1109/iecbes.2014.7047654

Cited by 13 publications

(12 citation statements)

References 16 publications

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“…An even layer is set by an auxiliary handling of silicon surface through APTES. Immobilization of APTES-COOH taking place on thin TiO 2 film displayed advance in flow of current changing from 0.2l µA near to 0.8l µA for an applied bias potential of 0.2 V -1 V. The flow of current in the experiment [10] exhibited that for an applied bias voltage of 0.8 V, the variation in current is of 0.6 µA. In the direction to increase the HPV sensing activity, it is Substrate Bottom gate…”

Section: (4)mentioning

confidence: 84%

“…x 4 CNTFET array gives better result series 2 in comparison with the series 1 reference work [10]. The current values varies from 4.286 µA to 15.435 µA for gate voltage varied from 0.2 V to 1.06 V as shown in figure 4.…”

Section: Improved Sensor Array Designmentioning

confidence: 92%

“…The 32 nm CNTFET electrical properties of are quicker and capable of handling greater currents in the range of 70 µA. Grounded on the considerations offered in [10] for biosensor design, in this effort, an innovative architecture is considered using CNTFET. The integration of DNA with nanobiosensor is designed to detect HPV.…”

Section: (4)mentioning

confidence: 99%

“…The 32 nm CNTFET offers faster and high current in the range of 70 µA. Established on the findings existing in [10] for the biosensor design, in this research activity, an innovative design is employed using CNTFET. In the reference research activity an arrays sensor network and control unit to detect cancer is discussed in [14].…”

Section: Top Gatementioning

confidence: 99%

“…It is faster and consumes less power than silicon transistor, which makes it ideal device for high frequency and lower power applications [12]. The biopotential of equivalent which is generated with chemical response of antigen with antibody is referred from [21,10] as well as it is used in the improved 64 CNTFET sensor array and is simulated using Hspice. The biosensor response is shown in figure 4.…”

Section: Improved Sensor Array Designmentioning

confidence: 99%

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HPV Sensing by CNTFET Array Nanobiosensor.

R¹,

Rao²

2018

IJET

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Women life is threatened by the cervical cancer each time worldwide. The cervical cancer high grade pre cancer is due to HPV E6 and E7 agents. Nano materials show a key role in medical analysis and action. CNTs (Carbon Nano Tube) have very unique electrical and mechanical properties which are useful in the bio-application. The conventional based biosensors can be improved by CNT based biosensors with respect to sensitivity, selectivity and simple in operation. In comparison with the silicon transistors, CNTFET (Carbon Nano Tube Field Effect Transistor) nano device takes less power and performs faster. The research paper covers working of CNTFET based nano biosensor to detect cervical cancer antibody. 4 x 4 CNTFET sensor array is designed to detect antibody variations on CNTFET gate. The sensor current varied from 4.286 µA to 15.435 µA for gate voltage varied from 0.2 V to 1.06 V. The improved 64 CNTFET based biosensor performs better in sensing the analyte of different concentrations.

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Section: (4)mentioning

confidence: 84%

Section: Improved Sensor Array Designmentioning

confidence: 92%

Section: (4)mentioning

confidence: 99%

Section: Top Gatementioning

confidence: 99%

Section: Improved Sensor Array Designmentioning

confidence: 99%

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HPV Sensing by CNTFET Array Nanobiosensor.

R¹,

Rao²

2018

IJET

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Design of biosensor array with current boost and signal conditioning circuits for HPV detection

Gopinath

Anitha²,

Mastani

2018

Alexandria Engineering Journal

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Nucleic aptamer modified porous reduced graphene oxide/MoS2 based electrodes for viral detection: Application to human papillomavirus (HPV)

Chekin

Bagga

Subramanian

et al. 2018

Sensors and Actuators B: Chemical

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Next to graphene nanomaterials, molybdenum disulfide (MoS 2 ) offers large surface area that can enhance its biosensing performance. In this work, we investigate the performance of glassy carbon (GC) electrodes modified successively with porous reduced graphene oxide (prGO) and molybdenum sulfide (MoS 2 ) for the sensitive and selective detection of the L1major capsid protein of human papilloma virus (HPV). Owing to the difficulties to perform serological assays and HPV cultures efficiently, tools based on molecular recognition are becoming of great importance. We developed here an electrochemical sensor for HPV upon covalent functionalization of the electrode with an aptamer Sc5-c3, a RNA aptamer targeted against the HPV-16 L1 protein. Using differential pulse voltammetry (DPV) and an optimized

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Rapid and sensitive strategy for Human Papillomavirus (HPV) detection using a gene-based DNA nanobiosensor

Cited by 13 publications

References 16 publications

HPV Sensing by CNTFET Array Nanobiosensor.

HPV Sensing by CNTFET Array Nanobiosensor.

Design of biosensor array with current boost and signal conditioning circuits for HPV detection

Nucleic aptamer modified porous reduced graphene oxide/MoS2 based electrodes for viral detection: Application to human papillomavirus (HPV)

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