Rapid and sensitive label-free determination of aflatoxin M1 levels in milk through a White Light Reflectance Spectroscopy immunosensor

Tsounidi, Dimitra; Koukouvinos, Georgios; Petrou, Panagiota; Μισιακός, Κωνσταντίνος; Zisis, G.; Goustouridis, D.; Raptis, Ioannis; Kakabakos, Sotirios

doi:10.1016/j.snb.2018.11.026

Cited by 25 publications

(18 citation statements)

References 40 publications

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“…Immobilization of mouse IgG and blocking of the chip surface was performed as described in sections 2.5 and 2.6 for chips modified with APTES or APTES/ glutaraldehyde, respectively. The chips were then assembled with a fluidic cover that allowed the monitoring of bioreactions taking place onto the chip surface under continuous flow conditions (Koukouvinos et al, 2016; Tsounidi et al, 2019). The chips were then placed on a docking station and positioned under the reflection probe of the white light interference spectroscopy (WLRS) set‐up developed by ThetaMetrisis SA.…”

Section: Methodsmentioning

confidence: 99%

Functionalization of silicon dioxide and silicon nitride surfaces with aminosilanes for optical biosensing applications

et al. 2020

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Section: Methodsmentioning

confidence: 99%

Functionalization of silicon dioxide and silicon nitride surfaces with aminosilanes for optical biosensing applications

et al. 2020

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“…A miniaturized optical immunosensor based on White Light Reflectance Spectroscopy (WLRS) has been described for sensitive detection of AFM1 in milk [59]. Silicon chip with a SiO 2 layer on top was covered with AFM1 -bovine serum albumin (BSA) conjugate.…”

Section: Other Sensors For Mycotoxin Determinationmentioning

confidence: 99%

Electrochemical Immuno- and Aptasensors for Mycotoxin Determination

Evtugyn

Hianik

2019

Chemosensors

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Modern analysis of food and feed is mostly focused on development of fast and reliable portable devices intended for field applications. In this review, electrochemical biosensors based on immunological reactions and aptamers are considered in the determination of mycotoxins as one of most common contaminants able to negatively affect human health. The characteristics of biosensors are considered from the point of view of general principles of bioreceptor implementation and signal transduction providing sub-nanomolar detection limits of mycotoxins. Moreover, the modern trends of bioreceptor selection and modification are discussed as well as future trends of biosensor development for mycotoxin determination are considered.

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“…Conversely, the AFT-albumin adduct with a longer half-life of www.bosaljournals/chemint/ editorci@bosaljournals.com 30-60 days, relative stability and minimum variability can be estimated in peripheral blood to measure the long-term AFT exposure (Williams et al, 2004). Results revealed that various factors are responsible for AFTs production and all living organisms are vulnerable for its toxic effects (Asare Bediako et al, 2019;Blankson et al, 2019;Cheng et al, 2019;Dí az Nieto et al, 2019;Frisvad et al, 2019;Gummadidala et al, 2019;Hamza et al, 2019;Magzoub et al, 2019;Mwakinyali et al, 2019;Shahbazi and Shavisi, 2019;Singh and Cotty, 2019;Tsounidi et al, 2019;Wang et al, 2019a;Wang et al, 2019b;Wu et al, 2019;Xie et al, 2019a;Xie et al, 2019b;Yu et al, 2019;Zeng et al, 2019;Zhao et al, 2019;Zhou et al, 2019). So far, there is need to develop the detoxification methods to save food and feed items without harming the nutritional and sensory characteristics.…”

Section: Detection and Exposure Assessment Of Aftsmentioning

confidence: 99%

Aflatoxins biosynthesis, toxicity and intervention strategies: A review

Int¹

2019

Preprint

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Aflatoxins (AFTs) are toxic products of fungal metabolism, associated with serious health consequences and substantial economic losses to agriculture, livestock and poultry sectors, particularly in the developing countries. This review outlines the current information on AFTs in terms of historical background, classification, relative occurrence and co-existence with other mycotoxins in various food commodities. The phenomenon of aflatoxin (AFT) biosynthesis has been elucidated with reference to molecular basis, genetic regulation and factors affecting the AFT production. Moreover, the in vivo disposition kinetics, toxicological action and toxico-pathological consequences of AFTs have also been highlighted. Currently employed strategies for the detection and detoxification of AFTs, biomarkers of exposure assessment, potential economic impact and regulatory considerations regarding the AFTs have been emphasized.

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Rapid and sensitive label-free determination of aflatoxin M1 levels in milk through a White Light Reflectance Spectroscopy immunosensor

Cited by 25 publications

References 40 publications

Functionalization of silicon dioxide and silicon nitride surfaces with aminosilanes for optical biosensing applications

Functionalization of silicon dioxide and silicon nitride surfaces with aminosilanes for optical biosensing applications

Electrochemical Immuno- and Aptasensors for Mycotoxin Determination

Aflatoxins biosynthesis, toxicity and intervention strategies: A review

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