Rapid and highly sensitive high-performance liquid chromatographic method for the determination of histamine and 3-methylhistamine in biological samples using fluorescamine as the derivatizing agent

Haaster, Charles M.C.J. van; Engels, W.; Lemmens, P. J. M. R.; Hornstra, Gerard; Vusse, Ger J.

doi:10.1016/0378-4347(94)80098-7

Cited by 9 publications

(8 citation statements)

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“…In addition, it requires carefully controlled reaction conditions [21]. Moreover, the OPA-derivatized products have a limited stability [22]. With regard to the HPLC postcolumn OPA derivatization methods, suYcient sensitivity and resolution for the measurement of brain HA and tele-MHA levels were not yet achieved.…”

Section: Discussionmentioning

confidence: 99%

“…Most of these systems measure HA and tele-MHA separately, whereas the HPLC coupled with precolumn OPA derivatization method was described as a simultaneous detection system of these amines [14]. However, the HPLC with precolumn derivatization method has the disadvantage of the relative instability of the derivatives and needs carefully controlled assay conditions [21,22]. Furthermore, the fact that the brain HA levels are relatively low and many biological amines concomitantly exist in the brain suggests that puriWcation and concentration steps prior to the column analysis might be beneWcial [23].…”

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confidence: 99%

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Simultaneous fluorometric measurement of histamine and tele-methylhistamine levels in rodent brain by high-performance liquid chromatography

Miyamoto

Yoshimoto

Yumoto

et al. 2004

Analytical Biochemistry

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Simultaneous fluorometric measurement of histamine and tele-methylhistamine levels in rodent brain by high-performance liquid chromatography

Miyamoto

Yoshimoto

Yumoto

et al. 2004

Analytical Biochemistry

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“…This compound was determined in supernatants of stimulated cells by High-Performance Liquid Chromatography as described in detail previously [14].…”

Section: Determination Of Histaminementioning

confidence: 99%

Dietary modulation of fatty acid composition of mast cell phospholipids does not affect histamine release induced by compound 48/80

Engels

Haaster

Lemmens

et al. 1997

Inflammation Research

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“…Histamine was determined in coronary effluents and cardiac tissue using High Performance Liquid Chromatography with fluorimetric detection as described previously [15].…”

Section: Determination Of Histaminementioning

confidence: 99%

Antigen-evoked mast cell degranulation in the isolated rat heart: No effect on subsequent ischemia-reperfusion induced damage

Engels

Haaster

Vleeming

et al. 1997

Inflammation Research

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In the present study, the possible role of mast cells in ischemia/reperfusion-induced myocardial injury was evaluated in the isolated 'mast cell depleted' rat heart. Hearts isolated from sensitized and non-sensitized rats were perfused according to Langendorff. After 30 min of normoxic perfusion, hearts were challenged with antigen, a procedure which is known to result in a massive mast cell degranulation in sensitized hearts. After another 20 min, both 'mast cell depleted' and control hearts were subjected to 30 min of ischemia followed by 30 min of reperfusion. The release of lactate dehydrogenase (LDH) was determined, to quantitate the extent of irreversible injury of cardiomyocytes. Histamine release was measured to establish mast cell degranulation. Coronary flow (CF) and left ventricular developed pressure (LVDP) were monitored to study the consequences of the procedures on hemodynamic recovery. It was found that both CF and LVDP significantly increased during the first min after antigen challenge. These changes were accompanied by an almost complete degranulation of cardiac mast cells. The increase in CF and LVDP values were rapidly followed by a decrease, reaching minimal values of 159 +/- 4% and 85 +/- 4% of those before administration of antigen, respectively, at 2-3 min after antigen challenge. No effect of antigen challenge on LDH release were found indicating that mast cell degranulation did not compromise myocyte integrity. During reperfusion following 30 min of ischemia both the increase in CF and LVDP in 'mast cell-depleted' hearts were not significantly different from those in control (non-sensitized) hearts. Similarly, at the end of the reperfusion-phase, CF and LVDP values in sensitized hearts were comparable to those in control hearts. Reperfusion results in increased LDH release, which at no point in time was significantly different between sensitized and non-sensitized hearts. In non-sensitized hearts histamine release during the reperfusion phase was not detectable. Therefore, the results indicate that in the isolated rat heart, mast cells are most likely not involved in acute ischemia/reperfusion-induced myocardial injury.

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Rapid and highly sensitive high-performance liquid chromatographic method for the determination of histamine and 3-methylhistamine in biological samples using fluorescamine as the derivatizing agent

Cited by 9 publications

References 1 publication

Simultaneous fluorometric measurement of histamine and tele-methylhistamine levels in rodent brain by high-performance liquid chromatography

Simultaneous fluorometric measurement of histamine and tele-methylhistamine levels in rodent brain by high-performance liquid chromatography

Dietary modulation of fatty acid composition of mast cell phospholipids does not affect histamine release induced by compound 48/80

Antigen-evoked mast cell degranulation in the isolated rat heart: No effect on subsequent ischemia-reperfusion induced damage

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