Raoultella ornithinolytica: An unusual pathogen for prosthetic joint infection

Seng, Piseth; Theron, F; Honnorat, Estelle; Prost, Didier; Fournier, Pierre‐Edouard; Stein, Andréas

doi:10.1016/j.idcr.2016.07.003

Cited by 11 publications

(9 citation statements)

References 7 publications

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“…Furthermore, the majority of cases responded adequately to treatment, the latter consisting usually of debridement and lavage of the affected joint and subsequent prolonged antimicrobial therapy. 69 Although response to standard treatment was frequently reported as satisfactory, amputation was previously required to control the infection. 69 While some cases may suggest that a prior intervention may have led to infection, other cases were described in immunocompetent patients with no identifiable entry points.…”

Section: Osteoarticular Infectionsmentioning

confidence: 99%

“…69 Although response to standard treatment was frequently reported as satisfactory, amputation was previously required to control the infection. 69 While some cases may suggest that a prior intervention may have led to infection, other cases were described in immunocompetent patients with no identifiable entry points. Nonetheless, osteoarticular manifestations account for a minority of infectious events with Raoultella ornithinolytica in the literature.…”

Section: Osteoarticular Infectionsmentioning

confidence: 99%

See 1 more Smart Citation

Raoultella ornithinolytica: Emergence and Resistance

Hajjar¹,

Ambaraghassi²,

Sebajang³

et al. 2020

IDR

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Raoultella ornithinolytica is an encapsulated Gram-negative, oxidase-negative, catalase-positive, aerobic, non-motile rod that belongs to the Enterobacteriaceae family. This bacterium was initially classified in the genus Klebsiella as Klebsiella ornithinolytica, until the creation of the genus Raoultella in 2001. R. ornithinolytica is usually found in water environments and soil, and due to its ability to convert histidine to histamine, it has been associated with histamine poisoning in humans. R. ornithinolytica is an emerging entity in human infections, with several reports of virulent infections in comorbid at-risk patients. Increasing reports are potentially due to better and more precise identification tools. The objective of this article is to provide a comprehensive review of reported cases of R. ornithinolytica infections, the emergent virulence of described multiresistant strains, and an overview of currently used identification methods.

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Section: Osteoarticular Infectionsmentioning

confidence: 99%

Section: Osteoarticular Infectionsmentioning

confidence: 99%

Raoultella ornithinolytica: Emergence and Resistance

Hajjar¹,

Ambaraghassi²,

Sebajang³

et al. 2020

IDR

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show abstract

“…12 De R. ornithinolytica se destaca su capacidad para adherirse a las superficies tisulares y formar biofilms, lo que explica las infecciones relacionadas con el uso de catéteres urinarios, venosos y dispositivos ortopédicos. 7 En nuestro caso, los factores de riesgo para el desarrollo de sepsis son variados: portador del catéter venoso central permanente, alteración de la microbiota intestinal y translocación bacteriana secundaria a patología de base.…”

Section: Discussionunclassified

“…6 Es causante de bacteriemia, infección del tracto urinario (ITU), IPTB, meningitis, mediastinitis, pericarditis, osteomielitis, infecciones del tracto biliar, 6 conjuntivitis e incluso otitis. 7 Las infecciones por dichos gérmenes son muy infrecuentes tanto en la población general como en pediatría. 4 Se presenta nuestra experiencia con estos microorganismos de la familia Enterobacteriaceae en un paciente con enfermedad mitocondrial.…”

Section: Introductionunclassified

Infección asociada a catéter por Leclercia adecarboxylata y Raoultella ornithinolytica en un paciente con enfermedad mitocondrial

et al. 2019

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RESUMENLeclercia adecarboxylata y Raoultella ornithinolytica constituyen bacterias Gram-negativas emergentes. Los casos descritos son excepcionales. En los últimos años, las mejoras en las técnicas de diagnóstico microbiológico han permitido su detección y conocimiento. Se presenta el caso de un niño de 11 años con enfermedad mitocondrial, portador de catéter venoso central de larga duración, que desarrolló dos episodios de sepsis por L. adecarboxylata y R. ornithinolytica, respectivamente. En los casos de infección asociada al uso de catéter, es posible, en ocasiones, el tratamiento sin su retirada con evolución favorable. Es importante reconocer L. adecarboxylata y R. ornithinolytica como patógenos de diagnóstico cada vez más frecuentes, sobre todo, en pacientes inmunodeprimidos o con patologías crónicas asociadas. Palabras clave: sepsis, Enterobacteriaceae, infecciones relacionadas con catéteres, enfermedades mitocondriales, pediatría.ABSTRACT Leclercia adecarboxylata and Raoultella ornithinolytica are emergent Gram-negative bacteria. Infections caused by these microorganisms are exceptional. Improvement of microbiologist techniques in the last years has enabled their detection and more accurate knowledge. We present the case of an 11-year-old boy with mitochondrial disease with a longterm central catheter who suffered from two sepsis caused by L. adecarboxylata and R. ornithinolytica, respectively. In catheter-related infections, sometimes it is possible to provide antimicrobial treatment without removal of catheter with good results, as in our patient. It is important to recognize L. adecarboxylata and R. ornithinolytica like increasingly frequent pathogenic bacteria, mostly in immunocompromised or chronic patients.

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“…These patients were considered to be at a great risk for this particular infection. Septic arthritis and sepsis in general [6,7] is possibly a major clinical consequence of this bacterial infection [8,9]. Children, especially in immunocompromised conditions are vulnerable in manifesting clinically significant complicated infections [10].…”

Section: Discussionmentioning

confidence: 99%

Clinical significance of positive Raoultella Ornithinolytica and Staphylococcus hominis cultures in a post lobectomy patient. A case report

Papakanderaki

Kanakakis

Goule

et al. 2018

Monaldi Arch Chest Dis

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Raoultella ornithinolytica is an encapsulated, Gram-negative, nonmotile aerobic rob which was reclassified from Klebsiella genus belonging to the family of Enterobacteriaceae. It is a rare human infection and few cases have been reported in post thoracotomy patients. Here we present a case of a left lower lobectomy patient that was complicated by pleural effusion, high fever with positive sputum cultures of Raoultella ornithinolytica and positive pleural fluid cultures of Staphylococcus hominis. The disease is related with aquatic life poisoning. There are few cases reported and even fewer postoperatively. The infection is rare in humans therefore the bacteria is still underreported.

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Raoultella ornithinolytica: An unusual pathogen for prosthetic joint infection

Abstract: We herein report the first case of a prosthetic joint infection caused by Raoultella ornithinolytica in an immunocompetent patient. The clinical outcome was favorable after a two-stage prosthetic exchange and a six-month course of antimicrobial therapy.

Cited by 11 publications

References 7 publications

<p><em>Raoultella ornithinolytica</em>: Emergence and Resistance</p>

<p><em>Raoultella ornithinolytica</em>: Emergence and Resistance</p>

Infección asociada a catéter por Leclercia adecarboxylata y Raoultella ornithinolytica en un paciente con enfermedad mitocondrial

Clinical significance of positive Raoultella Ornithinolytica and Staphylococcus hominis cultures in a post lobectomy patient. A case report

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