Clinical significance of positive Raoultella Ornithinolytica and Staphylococcus hominis cultures in a post lobectomy patient. A case report

Abstract

Raoultella ornithinolytica is an encapsulated, Gram-negative, nonmotile aerobic rob which was reclassified from Klebsiella genus belonging to the family of Enterobacteriaceae. It is a rare human infection and few cases have been reported in post thoracotomy patients. Here we present a case of a left lower lobectomy patient that was complicated by pleural effusion, high fever with positive sputum cultures of Raoultella ornithinolytica and positive pleural fluid cultures of Staphylococcus hominis. The disease is related with aquatic life poisoning. There are few cases reported and even fewer postoperatively. The infection is rare in humans therefore the bacteria is still underreported.

Integrated microbiome, metabolome and transcriptome profiling reveals the beneficial effects of fish oil and Bacillus subtilis jzxj-7 on mouse gut ecosystem

“…68 Raoultella, Staphylococcus and Escherichia-Shigella were significantly positively correlated with colonic LPS, isolithocholic acid and deoxycholic acid levels, Cxcl13, Cxcl10 and Nfkbil1 gene expression, indicating that these opportunistic pathogens promote inflammationrelated gene expression by accumulating harmful metabolites. 69 To summarize, FO and B. subtilis jzxj-7 supplementation boosted beneficial taxa and their derived SCFA levels, limited the pathogenic bacterial growth and concentrations of harmful metabolites, thereby down-regulating inflammationrelated genes and pro-inflammatory lipid mediator gene expression. These results suggest that the beneficial effect of the FO and B. subtilis jzxj-7-based diet is attributable to the modulation of the gut ecosystem.…”