Randomized controlled trial of a bioabsorbable steroid‐releasing implant in the frontal sinus opening

Abstract

1b. Laryngoscope, 126:2659-2664, 2016.

Evolution of the endoscopic modified Lothrop procedure: A systematic review and meta‐analysis

“…In a recent report, drug-eluting stents reduced requirements for postoperative interventions in frontal sinus surgery. 38 However, this study did not include EMLP patients, and there are insufficient numbers of other reports to draw any conclusions regarding the role of drug-eluting stents at this time.…”

“…Although stenting has not been shown historically to reduce the rate of postoperative stenosis, newer drug‐eluting stents may show promise. In a recent report, drug‐eluting stents reduced requirements for postoperative interventions in frontal sinus surgery . However, this study did not include EMLP patients, and there are insufficient numbers of other reports to draw any conclusions regarding the role of drug‐eluting stents at this time.…”

Randomized controlled trial of steroid‐soaked absorbable calcium alginate nasal packing following endoscopic sinus surgery

“…Although the cause of such timing difference remains uncertain, it may have been related to a healing process. Furthermore, it is much less expensive than a steroid‐eluting sinus stent, so its cost‐benefit ratio would be reasonable. Hong et al postulated that triamcinolone‐impregnated nasal dressings show low cortisol level systemic effects that recover gradually and normalize 10 days after the operation .…”

Topical therapies for management of chronic rhinosinusitis: steroid implants

“…A clinical study was performed evaluating a smaller variation of Propel for the safety and effectiveness in the management of postoperative frontal sinus disease and frontal sinusotomy. 13 This was a prospective randomized blinded controlled study comparing frontal sinuses that received a Propel Mini sinus implant with the contralateral frontal sinus receiving no implant in a total 80 patients undergoing the same endoscopic frontal sinus surgery for CRS. The frontal sinus openings were evaluated on day 30 postoperatively by clinical site investigators and an independent, blinded reviewer.…”

“…A prospective randomized double blinded study, n = 105 patients 45% reduction in nasal polyp, 62% reduction in synechiae, and 29% reduction in postsurgical interventions in study group compared to controls Smith et al 13 Randomized controlled trial of a bioabsorbable steroid-releasing implant in the frontal sinus opening.…”