Randomized, controlled surgical trial of preoperative tumor curettage of basal cell carcinoma in Mohs micrographic surgery

Huang, Conway C.; Boyce, Sarah; Northington, Marian; Desmond, Reneé A.; Soong, Seng‐Jaw

doi:10.1016/j.jaad.2004.04.009

Cited by 33 publications

(14 citation statements)

References 9 publications

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“…In a prospective, controlled study by Huang and colleagues, 166 patients with BCCs of the head and neck were randomized into curettage or no curettage arms before MMS. They found that there was a statistically significant difference between the surface area of the postsurgical defect and the area of the presurgical site for the curettage and no curettage arms but that there were fewer stages needed for tumor clearance in the curettage group 2 . In another study by Chung and colleagues, histological analysis of the presurgical curettage margin and the noncurettage margin of individual tumors revealed that presurgical curettage appropriately increased the stage one size in the vast majority of their cases.…”

Section: Discussionmentioning

confidence: 99%

A Direct Comparison of Visual Inspection, Curettage, and Epiluminescence Microscopy in Determining Tumor Extent Before the Initial Margins Are Determined for Mohs Micrographic Surgery

Guardiano¹,

Grande²

2010

Dermatologic Surgery

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There has been controversy as to whether presurgical curettage is appropriate before MMS. Some feel that curettage better delineates the tumor, leading to fewer stages, whereas others feel that curettage may falsely increase the final defect size, negating any tissue-sparing advantages of the procedure. Our study did not demonstrate any differences in the final number of stages or postoperative defect sizes between the three test groups.

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Section: Discussionmentioning

confidence: 99%

A Direct Comparison of Visual Inspection, Curettage, and Epiluminescence Microscopy in Determining Tumor Extent Before the Initial Margins Are Determined for Mohs Micrographic Surgery

Guardiano¹,

Grande²

2010

Dermatologic Surgery

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“…This method was used routinely in ophthalmology for imaging the retina but now the range of its usage has been spread to other cases including skin imaging. [10]…”

Section: Discussionmentioning

confidence: 99%

Comparison between examination with naked eye, curretage and dermoscopy in determining tumor extension before Mohs micrographic surgery

Asilian

Momeni

2013

Adv Biomed Res

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Mohs micrographic surgery (MMS) is a technique for the treatment of cutaneous malignancies. Subtle determination of tumor margin would end to fewer stages of surgery. Our aim was to compare these three ways for determining tumor extension before initiation of MMS, examination with the naked eye, dermoscopy and curettage. Sixty patients who had basal cell carcinoma (BCC) in head and neck area were randomized in three groups (curettage, dermoscopy and examination with the naked eye). Each group encompassed twenty patients. The total number of resection stages in MMS was recorded for each patient. Demographic data of the patients and the total number of resection stages in MMS were statistically analyzed. Based on analysis of variance (ANOVA) test results, there was no significant difference for total number of stages in statistical point of view between three groups (P value = 0.1). In this research, the Pearson correlation coefficient showed that there is a direct relation between the age and resection stages (r = 0.19, P value = 0.04). The Chi-square test showed no differences between three groups in age, residence and radiotherapy history.

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“…Importantly, there is no unintended enlargement of the defect. There is high‐level evidence that traditional curettage increases the size of Mohs defects . Neighbouring sun‐damaged but non‐malignant skin can be friable and curettes easily giving the impression of malignancy.…”

Section: Introductionmentioning

confidence: 99%

“…In these cases, curettage can yield poor‐quality specimens and less effective debulking. It has been recommended that curettage or debulking prior to MMS be avoided, a practice that has been widely adopted by Mohs surgeons.…”

Section: Introductionmentioning

confidence: 99%

Tangential excision debulking with vertical sections prior to Mohs micrographic surgery

Tucker¹,

Vinciullo

2019

Aust J Dermatology

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The tangential excision technique for removal of skin tumours has been previously described for truncal superficial BCCs but never before as an option for debulking prior to Mohs micrographic surgery (MMS). Tangential excision debulking with vertical sections represents an alternative to traditional curettage debulking and offers many advantages, most notably a far better tissue specimen for histopathological analysis.

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Randomized, controlled surgical trial of preoperative tumor curettage of basal cell carcinoma in Mohs micrographic surgery

Cited by 33 publications

References 9 publications

A Direct Comparison of Visual Inspection, Curettage, and Epiluminescence Microscopy in Determining Tumor Extent Before the Initial Margins Are Determined for Mohs Micrographic Surgery

A Direct Comparison of Visual Inspection, Curettage, and Epiluminescence Microscopy in Determining Tumor Extent Before the Initial Margins Are Determined for Mohs Micrographic Surgery

Comparison between examination with naked eye, curretage and dermoscopy in determining tumor extension before Mohs micrographic surgery

Tangential excision debulking with vertical sections prior to Mohs micrographic surgery

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