Randomized clinical trial of 270° posterior <i>versus</i> 180° anterior partial laparoscopic fundoplication for gastro-oesophageal reflux disease

Roks, David J.; Koetje, Jan H.; Oor, Jelmer E.; Broeders, Joris A.; Nieuwenhuijs, Vincent B.; Hazebroek, Eric J.

doi:10.1002/bjs.10500

Cited by 23 publications

(11 citation statements)

References 39 publications

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“…However, the main surgical techniques (full and semi-fundoplication) have similar associations with GERD. [39][40][41][42] The prevalence of GERD in the Nordic countries is similar to the prevalence in other Western countries but higher than in most developing countries, suggesting that the findings might be generalizable at least to other Western populations. 2,3 Immortal time bias or time-dependency of the exposure should not be major issues because patients were recruited from the date of GERD diagnosis, and not the date of surgery, and all person-time occurring within 1 year of inclusion were excluded.…”

Section: Discussionmentioning

confidence: 64%

“…There were no specific codes for separating different types of antireflux surgery. However, the main surgical techniques (full and semi-fundoplication) have similar associations with GERD 39–42 . The prevalence of GERD in the Nordic countries is similar to the prevalence in other Western countries but higher than in most developing countries, suggesting that the findings might be generalizable at least to other Western populations 2,3 .…”

Section: Discussionmentioning

confidence: 74%

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Esophageal Adenocarcinoma After Antireflux Surgery in a Cohort Study From the 5 Nordic Countries

et al. 2019

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Section: Discussionmentioning

confidence: 64%

Section: Discussionmentioning

confidence: 74%

Esophageal Adenocarcinoma After Antireflux Surgery in a Cohort Study From the 5 Nordic Countries

et al. 2019

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“…Subclassification of types of antireflux surgery was not possible due to lack of specific surgical codes, but the efficacy on GERD is similar across the main antireflux surgery techniques. [28][29][30][31] In the Nordic countries, the prevalence of GERD is higher than in most developing countries, but comparable to most other Western countries, 1,2 which suggests that the results could be generalized to Western populations. Finally, despite the large cohort size, the low incidence of laryngeal and pharyngeal squamous cell carcinoma (n = 39, 0.08%) reduced the statistical precision, particularly of some subgroup analyses.…”

Section: Discussionmentioning

confidence: 96%

Laryngeal and Pharyngeal Squamous Cell Carcinoma After Antireflux Surgery in the 5 Nordic Countries

et al. 2020

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The aim of this study was to clarify whether antireflux surgery prevents laryngeal and pharyngeal squamous cell carcinoma. Summary Background Data: Gastroesophageal reflux disease (GERD) seems to increase the risk of laryngeal and pharyngeal squamous cell carcinoma. Methods: All-Nordic (Denmark, Finland, Iceland, Norway, and Sweden) population-based cohort study of adults with documented GERD in 1980 to 2014. First, cancer risk after antireflux surgery was compared to the expected risk in the corresponding background population by calculating standardized incidence ratios (SIRs) with 95% confidence intervals (CIs). Second, cancer risk among antireflux surgery patients was compared to nonoperated GERD patients using multivariable Cox regression, providing hazard ratios (HR) with 95% CIs, adjusted for sex, age, calendar period, and diagnoses related to tobacco smoking, obesity, and alcohol overconsumption. Results: Among 814,230 GERD patients, 47,016 (5.8%) underwent antireflux surgery. The overall SIRs and HRs of the combined outcome laryngeal or pharyngeal squamous cell carcinoma (n = 39) were decreased after antireflux surgery [SIR = 0.62 (95% CI 0.44-0.85) and HR = 0.55 (95% CI 0.38-0.80)]. The point estimates were further decreased > 10 years after antireflux surgery [SIR = 0.48 (95% CI 0.26-0.80) and HR = 0.47 (95% CI 0.26-0.85)]. The risk estimates of laryngeal squamous cell carcinoma were particularly decreased > 10 years after antireflux surgery [SIR = 0.28 (95% CI 0.08-0.72) and HR = 0.23 (95% CI 0.08-0.69)], whereas no such decrease over time after surgery was found for pharyngeal squamous cell carcinoma. Analyses of patients with severe GERD (reflux esophagitis or Barrett esophagus) showed similar results. Conclusion: Antireflux surgery may decrease the risk of laryngeal squamous cell carcinoma and possibly also of pharyngeal squamous cell carcinoma.

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“…Of note, reoperations were observed more frequently after the latter [188]. When analyzing incomplete fundoplication, anterior and posterior fundoplication gave similar results in terms of symptom control, dysphagia frequency, and treatment satisfaction [203]. In other study, it has been shown that the posterior approach is more effective than the anterior approach, taking into account postoperatively observed reduced heartburn rate, reoperations frequency, and the need for PPIs [204].…”

Section: Surgical Treatmentmentioning

confidence: 73%

Diagnostic and therapeutic management in gastroesophageal reflux disease: consensus of the Polish Society of Gastroenterology

Świdnicka-Siergiejko¹,

Marek²,

Waśko−Czopnik³

et al. 2022

Polish Archives of Internal Medicine

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The following paper was developed by an expert group appointed by the Polish Society of Gastroenterology with the goal to update and systematize the knowledge about the diagnosis and treatment of gastroesophageal reflux disease (GERD). Based on the previously published guidelines of international societies, expert consensuses, and recently published good quality data, we formulated 74 statements regarding the definition, diagnosis and treatment of GERD and assessed the level of acceptance of these statements as well as the reliability of data. We discuss in detail about the possibilities and limitations of available diagnostic methods and therapies, with particular emphasis on the diversity of gastroesophageal reflux symptoms and complications including Barrett's esophagus. Practical principles regarding interpretation of the diagnostic tests are presented. In addition, we discuss the indications for surgical treatment as well as the situations in which surgical treatment is not indicated with emphasis on the importance of preoperative diagnostics. The role for add-on therapy and indications for maintenance treatment are defined.

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Randomized clinical trial of 270° posterior versus 180° anterior partial laparoscopic fundoplication for gastro-oesophageal reflux disease

Abstract: Both types of partial fundoplication provided similar control of GORD at 12 months, with no difference in post-fundoplication symptoms. Registration number: NTR5702 (www.trialregister.nl).

Cited by 23 publications

References 39 publications

Esophageal Adenocarcinoma After Antireflux Surgery in a Cohort Study From the 5 Nordic Countries

Esophageal Adenocarcinoma After Antireflux Surgery in a Cohort Study From the 5 Nordic Countries

Laryngeal and Pharyngeal Squamous Cell Carcinoma After Antireflux Surgery in the 5 Nordic Countries

Diagnostic and therapeutic management in gastroesophageal reflux disease: consensus of the Polish Society of Gastroenterology

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