Ramsay Hunt syndrome following mRNA SARS-COV-2 vaccine

Martín, Miguel Ángel Hernández; Corriols-Noval, Patricia; López-Simón, Eugenia; Morales‐Angulo, Carmelo

doi:10.1016/j.eimce.2021.06.003

Cited by 4 publications

(2 citation statements)

References 6 publications

(5 reference statements)

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“…Both VZV reactivation and facial paralysis were reported with virus vaccinations like hepatitis B and influenza vaccines [11].Hence, it's not astonishing that cases of both conditions be reported in relation to COVID-19 vaccination while the mechanism is still obscure.…”

Section: Discussionmentioning

confidence: 99%

Varicella-Zoster Virus reactivation following COVID-19 vaccination: A Tunisian case series

Ferchichi

Aouinti

Zaiem

et al. 2023

Preprint

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Introduction: Reactivation of varicella-zoster virus (VZV) most commonly manifests as shingles. A few months after the start of the COVID-19 vaccination campaign cases of shingles were reported. Objective: We aimed to report cases of VZV reactivation reported after COVID-19 vaccination to the Tunisian National Centre of pharmacovigilance (NCPV). Method: This is a retrospective study of cases of VZV reactivation reported to the CNPV after COVID-19 vaccination from March 2021 to May 2022. Results: We included 20 patients with shingle. The sex ratio (M/F) was 0.8. The median age was 68.5 years. Nine patients were over 70 years of age. The administered vaccines were an mRNA vaccine for 15 patients. The onset delay ranged between one and 30 days (mean of 4.5 days). All patients recovered within a few days and no severe cases have been reported. Two patients received the second dose; One patient did not experience a recurrence of the symptomatology. The other patient, had aggravation of symptomatology and occurrence of facial paralysis; noting that the initial symptomatology did not entirely disappear when the patient received the second dose. The patient was diagnosed with Ramsay Hunt Syndrome. Conclusion: Our study draws attention to the chronological association between SARS-CoV-2 vaccine and VZV reactivation, which should be investigated.

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Section: Discussionmentioning

confidence: 99%

Varicella-Zoster Virus reactivation following COVID-19 vaccination: A Tunisian case series

Ferchichi

Aouinti

Zaiem

et al. 2023

Preprint

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“…ist die Inzidenz einer idiopathischen Fazialisparese infolge einer COVID-19 jedoch signifikant höher als nach der Impfung [ 16 ]. Ein zeitlicher Zusammenhang zwischen dem Ramsay-Hunt-Syndrom selbst und der mRNA-SARS-CoV-2-Impfung wurde bisher nur einmalig bei einer erwachsenen, 78-jährigen Patientin beschrieben [ 14 ]. Gründe für die niedrige Fallzahl könnten die geringe zeitliche Latenz seit der Impfeinführung, aber auch fehlende Meldungen von vergleichbaren Fällen sein.…”

Section: Diskussionunclassified

Periphere Fazialisparese und Bläschen am Ohr nach einer Impfung

Bobinger-Girke

Steidl

Schnelke

2022

Monatsschr Kinderheilkd

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After the Storm: Ophthalmic Manifestations of COVID-19 Vaccines

Sen

Honavar

2021

Indian J Ophthalmol

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Several COVID-19 vaccines have been developed and approved for use around the world from December 2020, to combat the pandemic caused by the novel SARS-CoV-2 virus. Several ophthalmic manifestations of the COVID-19 vaccines have been reported by ophthalmologists. This review was undertaken to recognize, encourage active reporting and determine the pathogenesis and time of appearance for better awareness and understanding of the ophthalmic manifestations of COVID-19 vaccines. A literature search was performed for publications on the ophthalmic manifestations of COVID-19 vaccines between January 1, 2021 and November 7, 2021. 23 case reports, 17 letters to editors, 3 ophthalmic images, 4 brief communications, 4 retrospective cohort studies and 2 case control studies were included. Posterior segment, including the uvea, choroid and retinal vasculature, was most commonly affected and the reported clinical features developed at a median of four days from the time of vaccination. The possible mechanisms include molecular mimicry of the vaccine components with host ocular tissues, antigen-specific cell and antibody-mediated hypersensitivity reactions to viral antigens and adjuvants present in the vaccines. The causal relationship of the ocular signs and symptoms and COVID-19 vaccines has not been established and requires long-term and large multicentre data. Most of the reported manifestations are mild, transient and adequately treated when diagnosed and managed early. The benefits of COVID-19 vaccination outweighs the reported rare adverse events and should not be a deterrent to vaccination.

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Ramsay Hunt syndrome following mRNA SARS-COV-2 vaccine

Cited by 4 publications

References 6 publications

Varicella-Zoster Virus reactivation following COVID-19 vaccination: A Tunisian case series

Varicella-Zoster Virus reactivation following COVID-19 vaccination: A Tunisian case series

Periphere Fazialisparese und Bläschen am Ohr nach einer Impfung

After the Storm: Ophthalmic Manifestations of COVID-19 Vaccines

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