Ramipril induced polyserositis with pericardial tamponade and pleural effusion

Brunkhorst, Frank M.; Bloos, Frank; Klein, Reinhild

doi:10.1016/j.ijcard.2004.05.063

Cited by 8 publications

(6 citation statements)

References 5 publications

(6 reference statements)

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“…Brunkhorst reported ramipril-induced polyserositis involving the pleura and the pericardium. [2] In vitro LTT results correlated with the clinical course and supported the theory of immune modulation. As far as we know, our case is only the third case report of ACEI-induced PE, and the first with cilazapril.…”

Section: Discussionsupporting

confidence: 55%

“…[24] Yoshida has reported a case of imidapril-induced eosinophilic PE with eosinophilia. [4] The diagnosis was established on clinical and laboratory grounds as well as by the response to withdrawal of the drug.…”

Section: Discussionmentioning

confidence: 99%

“…Apart from the fact that pleural fluid lymphocytosis was present and eosinophilia was absent, our hypothesis is also supported by Brunkhorst’s observation. [2]…”

Section: Discussionmentioning

confidence: 99%

“…The presumed mechanisms for the effusion include hypersensitivity or allergic reaction, direct toxic effect, oxygen free radical production, suppression of antioxidant defense, chemical pleuritis, and immune modulation. [12] Drugs are also known to cause a lupus-like syndrome that can manifest with PE. [3]…”

mentioning

confidence: 99%

“…[24] We describe, what we believe is the first case of cilazapril (a novel ACEI)–induced lymphocytic PE.…”

mentioning

confidence: 99%

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Cilazapril-induced pleural effusion: A case report and review of the literature

Küpeli̇¹,

Ulubay²,

Ulaşlı³

et al. 2010

Ann Thorac Med

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We describe an unusual case of lymphocytic pleural effusion associated with the use of cilazapril, a novel angiotensin-converting-enzyme inhibitor (ACEI). An 80-year-old male was prescribed cilazapril for hypertension. He subsequently presented with right chest pain and dry cough. He was found to have a lymphocytic pleural effusion on thoracentesis. Extensive workup, including open pleural biopsy, failed to reveal the etiology of the effusion. However, soon after the withdrawal of cilazapril, his clinical symptoms improved and the effusion disappeared. ACEI-induced pleural effusion has only been rarely reported. Drug-induced pleural effusion should be considered when formulating the differential diagnosis in a patient receiving ACEI.

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Section: Discussionsupporting

confidence: 55%

Section: Discussionmentioning

confidence: 99%

“…Apart from the fact that pleural fluid lymphocytosis was present and eosinophilia was absent, our hypothesis is also supported by Brunkhorst’s observation. [2]…”

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

“…[24] We describe, what we believe is the first case of cilazapril (a novel ACEI)–induced lymphocytic PE.…”

mentioning

confidence: 99%

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Cilazapril-induced pleural effusion: A case report and review of the literature

Küpeli̇¹,

Ulubay²,

Ulaşlı³

et al. 2010

Ann Thorac Med

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Current awareness: Pharmacoepidemiology and drug safety

2005

Pharmacoepidemiology and Drug

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In order to keep subscribers up‐to‐date with the latest developments in their field, John Wiley & Sons are providing a current awareness service in each issue of the journal. The bibliography contains newly published material in the field of pharmacoepidemiology and drug safety. Each bibliography is divided into 20 sections: 1 Books, Reviews & Symposia; 2 General; 3 Anti‐infective Agents; 4 Cardiovascular System Agents; 5 CNS Depressive Agents; 6 Non‐steroidal Anti‐inflammatory Agents; 7 CNS Agents; 8 Anti‐neoplastic Agents; 9 Haematological Agents; 10 Neuroregulator‐Blocking Agents; 11 Dermatological Agents; 12 Immunosuppressive Agents; 13 Autonomic Agents; 14 Respiratory System Agents; 15 Neuromuscular Agents; 16 Reproductive System Agents; 17 Gastrointestinal System Agents; 18 Anti‐inflammatory Agents ‐ Steroidal; 19 Teratogens/fetal exposure; 20 Others. Within each section, articles are listed in alphabetical order with respect to author. If, in the preceding period, no publications are located relevant to any one of these headings, that section will be omitted.

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Pleurotoxic Drugs—an Update: Someone Else to Blame?

Skouras

Kalomenidis

2019

Curr Pulmonol Rep

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Ramipril induced polyserositis with pericardial tamponade and pleural effusion

Cited by 8 publications

References 5 publications

Cilazapril-induced pleural effusion: A case report and review of the literature

Cilazapril-induced pleural effusion: A case report and review of the literature

Current awareness: Pharmacoepidemiology and drug safety

Pleurotoxic Drugs—an Update: Someone Else to Blame?

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