RAGE Gene Polymorphisms Are Associated with Circulating Levels of Endogenous Secretory RAGE but Not with Coronary Artery Disease in Chinese Patients with Type 2 Diabetes Mellitus

The Interaction Between Obesity and RAGE Polymorphisms on the Risk of Knee Osteoarthritis in Chinese Population

“…This is a major limitation of this study. Two studies reported higher GG distribution (between 47%-63%GG prevalence) in Chinese cohorts [18,30], However, our study showed a lower GG frequencies (between 20%-26%). In contrast, the SS genotype rate in our study was higher in our study.…”

Association of RAGE gene polymorphisms with type 2 diabetes mellitus, diabetic retinopathy and diabetic nephropathy

“…We identified 29 articles (Balasubbu et al, 2010;dos Santos et al, 2005;Gao et al, 2007;Globocnik Petrovic et al, 2003;Goulart et al, 2008;Hudson et al, 1998Hudson et al, , 2001Kankova et al, 1999Kankova et al, , 2001aKankova et al, ,b, 2002Kankova et al, , 2005Kumaramanickavel et al, 2002;Liu and Xiang, 2000;Lu et al, 2008;Matsunaga-Irie et al, 2004;Peng et al, 2009;Prasad et al, 2010;Ramprasad et al, 2007;Ren et al, 2003;Uthra et al, 2010;Xu et al, 2002Xu et al, , 2004Yang et al, 2003Yang et al, , 2008Yoshioka et al, 2005a,b;Zhang and Chen, 2008;Zhang et al, 2009)with 58 outcomes eligible for this meta-analysis, including 16 outcomes for T2DM, 6 outcomes for DR and 4 outcomes for DN considering Gly82Ser polymorphism; 6 outcomes for T2DM, 3 outcomes for DR and 4 outcomes for DN considering 1704 G/T polymorphism; 9 outcomes for T2DM, 5 outcomes for DR and 5 outcomes for DN considering 429 T/C polymorphism. All 29 articles were case-control designs.…”

The -374A Allele of the RAGE Gene As a Potential Protective Factor for Vascular Complications in Type 2 Diabetes: A Meta-Analysis

“…These articles were published between 2001 and 2009. Among them two articles (Lindholm et al 2006;Lu et al 2008) were excluded because they partially overlapped with the other two studies (Lindholm et al 2008;Peng et al 2009) that provided a larger data. In the rest of articles, one article described on two ethnic groups (Caucasian-and African-Brazilians) and three types of complications (DR, DN and ischemic heart disease) (dos Santos et al 2005).…”

“…After review, 11 articles investigating the association between the RAGE gene -374T/A polymorphism and vascular complications in T2DM met the inclusion criteria (Hudson et al 2001;Globocnik Petrovic et al 2003;JiXiong et al 2003;Kirbis et al 2004;dos Santos et al 2005;Kankova et al 2005;Lindholm et al 2006;Ramprasad et al 2007;Lindholm et al 2008;Lu et al 2008;Peng et al 2009). These articles were published between 2001 and 2009.…”