Radiotherapy of nasopharyngeal cancer using Rapidarc: dosimetric study of military teaching hospital Mohamed V, Morocco

Lalya, Issam; Marnouche, El Amin; Maghous, Abdelhak; Zaghba, Noha; Andaloussi, Khalid; Elmarjany, Mohamed; Baddouh, Laila; Dahmani, Keltoum; Hadadi, Khalid; Sifat, Hassan; Mansouri, Hamid

doi:10.1186/s13104-017-2430-2

Cited by 3 publications

(5 citation statements)

References 21 publications

(26 reference statements)

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“…Для описания клеточных потерь вследствие облучения предложен целый ряд математических моделей, из которых наиболее распространенной на сегодняшний день является линейно-квадратичная, предполагающая, что гибель клетки происходит в результате двойного нарушения спиралей ДНК, вероятность которого пропорциональна квадрату поглощенной дозы [7]. Для рано реагирующих на облучение тканей эта доза равна 7-20 Гр, для поздно реагирующих -0,5-6 Гр, что описано сфор-© Коллектив авторов, 2018 *Тел.…”

Section: лучевые реакции и повреждения возникающие у пациентов со знunclassified

“…

Многочисленными биологическими экспериментами доказано, что действие ионизирующего излучения реализуется путем нарушения структуры ДНК клеток с последующим возникновением летальных, сублетальных и потенциально летальных клинических повреждений, в зависимости от которых возникает либо гибель клеток, либо их инактивация при последующем облучении [1]. Лучевое лечение пациентов со злокачественными новообразованиями (ЗНО) челюстно-лицевой области (ЧЛО), оказывая положительное противоопухолевое действие, вызывает ряд лучевых реакций и повреждений [2, 3], в том числе отрицательно влияет на производство и качество слюны в больших и малых слюнных железах -СЖ [4-6].

Лучевые реакции и повреждения, возникающие у пациентов со ЗНО ЧЛОДля описания клеточных потерь вследствие облучения предложен целый ряд математических моделей, из которых наиболее распространенной на сегодняшний день является линейно-квадратичная, предполагающая, что гибель клетки происходит в результате двойного нарушения спиралей ДНК, вероятность которого пропорциональна квадрату поглощенной дозы [7]. Для рано реагирующих на облучение тканей эта доза равна 7-20 Гр, для поздно реагирующих -0,5-6 Гр, что описано сфор-© Коллектив авторов, 2018 *Тел.

…”

unclassified

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Radiation-associated changes in salivation of patients with cancer of maxillofacial region

Bykov¹,

Izhnina²,

Кочурова³

et al. 2018

Stomat.

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Section: лучевые реакции и повреждения возникающие у пациентов со знunclassified

“…

…”

unclassified

Radiation-associated changes in salivation of patients with cancer of maxillofacial region

Bykov¹,

Izhnina²,

Кочурова³

et al. 2018

Stomat.

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“…-Increased machine time required for quality assurance (QA) of complex IMRT plans for each patient and limitation of the number of patients who can be treated by treatment unit and increasing the patient waiting list. This is in addition to increased treatment cost in IMRT compared to 3D-CRT and cost related to time and to administrative and technical staff [1]. -Patient discomfort with increased risk of movement during treatment is also a limiting factor [30].…”

Section: Prolongation Of the Treatment Time Has Been Identified As Onmentioning

confidence: 99%

“…Prostate cancer is the most common cancer in men and is the second most common cause of cancer related death in men [1]. It is potentially curable if detected and treated in the early stages.…”

Section: Introductionmentioning

confidence: 99%

Comparison of intensity modulated and 3- dimensional conformal ‎radiotherapy for prostate cancer using ‎6-MV and 15-MV photon ‎energies

AL-Shareef

Attalla

Khalil

et al. 2020

Arab Journal of Nuclear Sciences and Applications

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Prostate cancer is one of the most common cancers in men. The purpose of this work is to compare between intensity-modulated radiotherapy (IMRT) versus three-dimensional conformal radiotherapy (3D-CRT) planning in patients with prostate cancer using 6-MV and 15-MV photon energies. Twenty patients with localized prostate cancer were planned on Xio treatment planning system. Four treatment plans were generated for each patient. IMRT whether 6 or 15 MV beam was slightly better in terms of target coverage, but not significant (p>0.05) in comparison to 3D-CRT in both beam energies. IMRT was better than 3D-CRT in terms of organs at risk (OARs) sparing and conformity index (CI) in both 6 and 15-MV whereas 3D-CRT in both 6 and 15-MV yielded better homogeneity index (HI) compared to IMRT 6 and 15-MV. The number of monitor units (MU) increased in IMRT compared to 3D-CRT. Also, MU increased in low energy compared to high energy whether in 3D-CRT or IMRT (p<0.05). When IMRT 6-MV and IMRT 15-MV were compared, no significant difference was found in terms of target coverage and OARs except the rectum which was better in IMRT 6-MV compared to IMRT 15-MV. IMRT 6-MV technique should be prioritized when user has options for treatment and then 3D-CRT as a second line when the former is not available. The choice of the energies (6 and 15MV) used with 3D-CRT depends largely on patient's body geometry, while the use of a high energy IMRT 15-MV is not recommended.

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“…The plan is a simple box technique with four 6-MV beams that are conformed with the help of MLC to the PTV. 15 IMRT was the second technique used on the eight patients in this study. It was also done in one phase, i.e.…”

Section: Two Types Of Treatment Planningmentioning

confidence: 99%

3D-Conformal Radiation Therapy and IntensityModulated Radiation Therapy Techniques for Laryngeal Cancer Taking Parotid Glands as Organ at Risk

Ismael

Hassan

2020

Hosp Pract Res

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Background: Three-dimensional conformal radiotherapy (3D-CRT) and intensity-modulated radiotherapy (IMRT) techniques are used for the treatment of patients with laryngeal cancer. Objective: This study aimed to investigate the effects of these 2 treatment techniques on the planning target volume (PTV) (laryngeal cancer), dose homogeneity, dose of organs at risk (OARs) (parotid glands), and conformity index. Methods: This study compared 2 treatment techniques and was conducted from October 2018 to April 2019 at the Zhianawa Cancer Center (ZCC), Sulaimaniyah, Iraq. Eight patients with laryngeal cancer were selected for this study. 3D-CRT and IMRT were used to produce the maximum dose of target volume coverage and minimum dose to the parotid glands. Elekta synergy with a photon beam of 6 MV was used for all measurements. Data analysis was performed using the available statistical package of SPSS 25. Results: The comparison of 3D-CRT with IMRT showed that the mean conformity index value for IMRT was more conformal than the 3D-CRT plan (0.956, 0.945, respectively), but the homogeneity index was better with 3D-CRT than with IMRT (0.175, 0.202, respectively). The mean dose for Rt. parotid glands was higher with IMRT than with 3D-CRT (232.71, 23.26, respectively), and in both plans the mean dose was less than 26 Gy (the standard tolerance value). While in the Lt. parotid gland the mean dose was higher with 3D-CRT than with IMRT (26.95, 23.71, respectively), the mean dose with 3D-CRT was greater than 26 Gy. The amount of PTV was significantly greater with the IMRT technique than with 3D-CRT (52.15±1.61, 51.09.4±0.74 Gy, respectively). Conclusion: This study further supports that IMRT has improved the long-term quality of life of patients with laryngeal cancer.

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Radiotherapy of nasopharyngeal cancer using Rapidarc: dosimetric study of military teaching hospital Mohamed V, Morocco

Cited by 3 publications

References 21 publications

Radiation-associated changes in salivation of patients with cancer of maxillofacial region

Radiation-associated changes in salivation of patients with cancer of maxillofacial region

Comparison of intensity modulated and 3- dimensional conformal ‎radiotherapy for prostate cancer using ‎6-MV and 15-MV photon ‎energies

3D-Conformal Radiation Therapy and IntensityModulated Radiation Therapy Techniques for Laryngeal Cancer Taking Parotid Glands as Organ at Risk

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