Radiotherapy in non-functioning pituitary macroadenoma: Mansoura experience

Wahba, Hanan Ahmed; El-Hadaad, Hend Ahmed; Elzahaf, Eman; Abu-Hegazy, Mohammad

doi:10.1007/s11805-011-0585-5

Cited by 1 publication

(3 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The decision to recommend radiation is based on the amount and location of the residual tissue by MRI, the aggressiveness of the adenoma, and the patient's age and general health. Per Wahba et al, conventional external RT up to 54 Gy is safe and effective in controlling nonfunctioning pituitary macroadenoma with tolerable and acceptable morbidity [ 19 ]. Stereotactic techniques such as stereotactic radiosurgery or fractionated stereotactic radiotherapy have more localized irradiation and fewer long-term side-effects [ 19 ].…”

Section: Discussionmentioning

confidence: 99%

“…Per Wahba et al, conventional external RT up to 54 Gy is safe and effective in controlling nonfunctioning pituitary macroadenoma with tolerable and acceptable morbidity [ 19 ]. Stereotactic techniques such as stereotactic radiosurgery or fractionated stereotactic radiotherapy have more localized irradiation and fewer long-term side-effects [ 19 ]. Both techniques provide excellent tumor control in patients with NFPAs, ranging from 85% to 95% at five to 10 years [ 19 ].…”

Section: Discussionmentioning

confidence: 99%

“…Stereotactic techniques such as stereotactic radiosurgery or fractionated stereotactic radiotherapy have more localized irradiation and fewer long-term side-effects [ 19 ]. Both techniques provide excellent tumor control in patients with NFPAs, ranging from 85% to 95% at five to 10 years [ 19 ].…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Acute Unilateral Oculomotor Nerve Palsy as the Initial Presenting Sign of Nonfunctioning Apoplectic Gonadotroph Adenoma

Gaballa

Lindsay

AlJaf

et al. 2020

Cureus

View full text Add to dashboard Cite

Pituitary macroadenoma usually presents with visual field defects. Oculomotor nerve palsy is a rare presentation, and usually a sign of para-sellar growth and cavernous sinus extension. The oculomotor nerve is more susceptible to laterally transmitted pressure by pituitary mass expansion because of its anatomical location. A slow onset oculomotor nerve palsy results from either gradual compression of the nerve in the sinus wall or direct infiltration of the nerve by the pituitary tumor. We are reporting a unique case of a 68-year-old African American patient who presented to an ophthalmology clinic with left eye complete ptosis, blurry vision, and a progressive headache for a few weeks. He was found to have a nonfunctioning pituitary adenoma (NFPA) that required urgent transnasal transsphenoidal tumor resection. The patient's ocular movements significantly improved a few days postoperatively, and repeated computed tomography (CT) of the head showed complete resection of the pituitary adenoma. The postoperative morning cortisol level was significantly low, confirming the diagnosis of secondary adrenal insufficiency. The patient was treated with corticosteroid replacement therapy.

show abstract

Section: Discussionmentioning

confidence: 99%