Radiothérapie hypofractionnée des cancers du rectum chez le sujet âgé

Vernat, S. Servagi; Guilbert, Philippe; Bouche, Gauthier; Ramiandrisoa, F.; Bellefqih, S.

doi:10.1016/j.canrad.2018.07.130

Cited by 2 publications

(1 citation statement)

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“…These patients and their physicians may therefore seek to avoid lengthy RT regimens and associated toxicities. Studies of breast, prostate, and rectal cancer treatment have investigated alternative fractionation regimens for elderly patients in effort to maintain efficacy and improve tolerability 40–42 . This may be a direction for future research in HNC, as highly conformal treatments, hypofractionation, and accessible supportive services may reduce toxicity and make RT a more tolerable and therefore more commonly selected treatment option for elderly patients who would benefit from it.…”

Section: Discussionmentioning

confidence: 99%

Equity in adjuvant radiotherapy utilization in locally advanced head and neck cancer: A SEER‐data based study

et al. 2023

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Background: Not all patients with locally advanced head and neck cancer (HNC) who are eligible for adjuvant radiotherapy (RT) following upfront surgery appear to receive it. Methods: Data were obtained from the Surveillance, Epidemiology, and End Results (SEER) database. Selected patients from 2009 to 2018 had locally advanced HNC, underwent upfront surgery, and were eligible for adjuvant RT. Multivariable logistic regression and chi-squared test were used to analyze available patient and tumor characteristics. Results: Of 12 549 patients, 84.5% underwent adjuvant RT, 15.5% did not.Characteristics associated with lowest adjuvant RT utilization included cancers of the larynx (p < 0.0001) and gingivae (p < 0.0001), age 80 and above (p < 0.0001), unpartnered status (p < 0.0001), and residence within a nonmetropolitan area (p < 0.0024). Conclusions: Tumor subsite, age, partnered status, and rural/urban residence correlate with omission of adjuvant RT in locally advanced HNC.

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Section: Discussionmentioning

confidence: 99%