“…A recent series including 36 radiation courses for leukemia cutis observed that complete response rate and local control were comparable in low-dose (≤26 Gy) and high-dose regimens although longer median duration of local control was seen in the >26 Gy cohort [11] . Doses of at least 20 Gy are recommended and some authors suggest 24 Gy in 12 fractions as a safe and optimal regimen [8] , [12] . AML patients showed better long-term outcomes compared with other types of leukemia [11] .…”
HighlightsIsolated chloroma should be considered as a systemic disease.Consolidation radiotherapy has been related with prolonged failure free survival.Excellent local control of chloroma is achieved with low-dose radiotherapy.
“…A recent series including 36 radiation courses for leukemia cutis observed that complete response rate and local control were comparable in low-dose (≤26 Gy) and high-dose regimens although longer median duration of local control was seen in the >26 Gy cohort [11] . Doses of at least 20 Gy are recommended and some authors suggest 24 Gy in 12 fractions as a safe and optimal regimen [8] , [12] . AML patients showed better long-term outcomes compared with other types of leukemia [11] .…”
HighlightsIsolated chloroma should be considered as a systemic disease.Consolidation radiotherapy has been related with prolonged failure free survival.Excellent local control of chloroma is achieved with low-dose radiotherapy.
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