Radiosynoviorthese und Röntgenstrahlentherapie

Mödder, Gynter

doi:10.1007/978-3-540-34105-5_19

Cited by 7 publications

(7 citation statements)

References 25 publications

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“…For the RS, different radioisotopes can be used. The selection of the radioisotope should take into account two parameters [4,11]: 1) physical properties: half-life, soft tissue penetration, size of the radiocolloid, 2) and clinical features: joint size, amount of joint fluid, synovial thickness. The material should also be a pure beta emitter, thereby minimizing the whole body exposure to gamma radiation [4,8,12,13].…”

Section: Methodsmentioning

confidence: 99%

Treatment with radiosynoviorthesis in hemophilic patients with and without inhibitor

et al. 2020

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Background: Spontaneous bleedings occurring into joints (hemarthrosis) are the most common manifestations of hemophilia and causes severe joint damage ultimately resulting in joint disfunction known as hemophilic arthropathy. Among available therapeutic options for reducing recurrent hemarthrosis-associated damage, radiosynoviorthesis (RS) has proven effective in improving joint function. Aim: To assess the impact of RS with Yttrium(90) citrate (C-Y(90)) on frequency of hemarthroses and joint function in a group of pediatric patients. Methods: Between November 1998 and February 2017, we evaluated 27 pediatric patients with mild, moderate or severe hemophilia with haemophilic arthropathy. Overall, RS was applied in 60 joints. Some patients received more than one single intra-articular injection with C-Y(90). Results: During the follow-up, one patient showed joint bleeding 15 months after RS, one patient after 12 months and one patient after 45 days. The episodes of hemarthrosis were reduced and joint function significantly improved in all patients. Conclusion: RS with C-Y(90) is a simple and safe treatment for reducing the frequency of hemarthroses in patients with hemophilia. It decreases the use of factor VIII / IX and improves joint function.

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Section: Methodsmentioning

confidence: 99%

Treatment with radiosynoviorthesis in hemophilic patients with and without inhibitor

et al. 2020

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Section: Methodsmentioning

confidence: 99%

Treatment with radiosynoviorthesis in hemophilic patients with and without inhibitor

Sanabria

Sato

Resendiz

et al. 2020

Preprint

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Background. Spontaneous bleedings occurring into joints (hemarthrosis) are the most common manifestations of hemophilia and causes severe joint damage ultimately resulting in joint disfunction known as hemophilic arthropathy. Among available therapeutic options for reducing recurrent hemarthrosis-associated damage, radiosynoviorthesis (RS) has proven effective in improving joint function. Aim. To assess the impact of RS with Yttrium(90) citrate (C-Y(90)) on frequency of hemarthroses and joint function in a group of pediatric patients. Methods . Between November 1998 and February 2017, we evaluated 27 pediatric patients with mild, moderate or severe hemophilia with haemophilic arthropathy. Overall, RS was applied in 60 joints. Some patientsreceived more than one single intra-articular injection with C-Y(90). Results. During the follow-up, one patient showed joint bleeding 15 months after RS, one patient after 12 months and one patient after 45 days. The episodes of hemarthrosis were reduced and joint function significantly improved in all patients. Conclusion. RS with C-Y(90) is a simple and safe treatment for reducing the frequency of hemarthroses in patients with hemophilia. It decreases the use of factor VIII / IX and improves joint function.

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“…Joint infection is very rare observing strict sterile injection technique and may be achievable even in less than the ''normal'' rate of 1: 35,000 joint punctures (Kaiser and Kley 1992;Mödder 2008).…”

Section: Side Effectsmentioning

confidence: 99%

Radionuclide Therapy of Inflammatory Joint Diseases (Radiation Synovectomy, Radiosynoviorthesis)

Mödder¹

2013

Therapeutic Nuclear Medicine

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Radiosynoviorthese und Röntgenstrahlentherapie

Cited by 7 publications

References 25 publications

Treatment with radiosynoviorthesis in hemophilic patients with and without inhibitor

Treatment with radiosynoviorthesis in hemophilic patients with and without inhibitor

Treatment with radiosynoviorthesis in hemophilic patients with and without inhibitor

Radionuclide Therapy of Inflammatory Joint Diseases (Radiation Synovectomy, Radiosynoviorthesis)

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