Radiosurgery

Steiner, Ladislau; Lindquist, C.; Steiner, Melita

doi:10.1007/978-3-7091-6672-7_2

Cited by 68 publications

(18 citation statements)

References 60 publications

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“…The effectiveness of GKRS in the treatment of benign and malignant intracranial tumors is well documented [11]. The use of GKRS for skull base invasion and malignant tumors of the skull base has also been reported [12± 14].…”

Section: Discussionmentioning

confidence: 99%

Gamma Knife Radiosurgery for Skull Base Metastasis and Invasion

Iwai¹,

Yamanaka²

1999

Stereotact Funct Neurosurg

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Section: Discussionmentioning

confidence: 99%

Gamma Knife Radiosurgery for Skull Base Metastasis and Invasion

Iwai¹,

Yamanaka²

1999

Stereotact Funct Neurosurg

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“…The results were good after a latency of up to 10 years. However, this was not true radiosurgery as defined by Leksell, since a hypofractionation technique, using 4 to 5 fractions was employed [12,33]. Backlund [34] was the first to attempt Gamma Knife radiosurgery for pituitary tumors in 1973.…”

Section: Discussionmentioning

confidence: 99%

Four Years’ Experiences in the Treatment of Pituitary Adenomas with Gamma Knife Radiosurgery

Lim

Leem

Kim

et al. 1998

Stereotact Funct Neurosurg

115

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To determine the tumor control rates and endocrinological responses after stereotactic radiosurgery for pituitary adenomas, we reviewed our experience in 65 patients (40 men, 25 women) treated in the Gamma Knife during the last 4 years. The mean age was 41.6 years (range 19–69 years). 43 patients had endocrinologically active tumors (20 growth hormone-secreting, 19 prolactin-secreting and 4 ACTH-secreting adenomas). 22 had nonfunctioning adenomas. 39 patients had a macroadenoma and 26 patients had a microadenoma. 33 patients underwent Gamma Knife radiosurgery for recurrent or residual tumors after microsurgery. 50 patients have had follow-up neuroimaging studies and/or hormonal evaluation. The follow-up period was 25.5 months (range 3 to 54 months). The margin of the tumor was incorporated within the 50 to 90% isodose. The mean number of isocenters was 3.8 and the mean marginal dose was 25.4 Gy (range 15 to 36 Gy). 27 out of 40 patients (65.7%) showed decreased tumor volume to less than 50% of the initial volume. In 17 out of 38 patients (44.7%) with endocrinologically active tumors, the hormonal level fell to within the normal range. Two patients had delayed complications: in one case there was pituitary insufficiency and in the other a visual disturbance. Gamma Knife radiosurgery seems to be effective adjuvant therapy for pituitary adenoma in selected cases. More long-term follow-up is required to evaluate the efficacy and side effects further.

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“…Furthermore, palliative surgical procedures such as multiple subpial transection and the formerly more common partial callosotomy have witnessed renewed interest [130,138,140,179,180,209,281]. Some centers have also evaluated new approaches such as radiosurgery for the treatment of partial epilepsy [170,171,172,173,227].…”

Section: Introductionmentioning

confidence: 99%

Presurgical evaluation and surgical treatment of medically refractory epilepsy

Siegel

2004

Neurosurgical Review

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Thanks to today's modern imaging examination techniques and especially to the common use of intracranial electrodes for localizing seizure foci, more and more patients with partial epilepsy can be treated microsurgically. The results of such neurosurgical therapies are very good, particularly in mesial temporal lobe epilepsy. In recent years, good results (60-70% seizure freedom) have also been achieved in extratemporal epilepsy surgery, so that such procedures can now be recommended for carefully selected patients. In this review, presurgical evaluations and the different surgical approaches are presented.

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Radiosurgery

Cited by 68 publications

References 60 publications

Gamma Knife Radiosurgery for Skull Base Metastasis and Invasion

Gamma Knife Radiosurgery for Skull Base Metastasis and Invasion

Four Years’ Experiences in the Treatment of Pituitary Adenomas with Gamma Knife Radiosurgery

Presurgical evaluation and surgical treatment of medically refractory epilepsy

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