Radionuclide evaluation of spontaneous femoral osteonecrosis.

Greyson, N D; Lotem, M; Gross, A E; Houpt, Joseph B.

doi:10.1148/radiology.142.3.7063692

Cited by 50 publications

(8 citation statements)

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“…This gives an overlap between the patella and the lateral femoral condyle. Lateral views are valuable in order to determine if a raised uptake emanates from the patella, femur or tibia (6,10). However, in our experience the lateral view in semiflexion is not always sufficient Accepted for publication 2 May 1988.…”

Section: Discussionmentioning

confidence: 95%

The Condyle View

1988

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Section: Discussionmentioning

confidence: 95%

The Condyle View

1988

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“…Since there are few, if any, radiologic findings in the early stage of ON of the knee despite the presence of severe pain, this may mislead physicians into making an erroneous diagnosis (18). Several investigators have recommended that MRI or bone scintigraphy be performed in order to make a precise diagnosis in the early stage of ON of the knee, when there are no distinct radiographic alterations (8, 23). Among the variables examined in our joint fluid analyses, we found that the ratio of C6S:C4S in ON knees was significantly higher throughout the developmental course of the disease, except for stage 4, than the ratio in OA knees.…”

Section: Discussionmentioning

confidence: 99%

Use of joint fluid analysis for determining cartilage damage in osteonecrosis of the knee

Saito¹,

Takeuchi²,

Mitsuhashi³

et al. 2002

Arthritis & Rheumatism

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Objective. To assess the value of joint fluid analysis for determining cartilage degradation and prognosis in spontaneous osteonecrosis (ON) of the knee. Results. The mean ؎ SD level of C6S was 82.2 ؎ 36.6 nmoles/ml in joint fluid from ON knees, which was significantly higher than the levels in knees with grade 2 (47.2 ؎ 20.0 nmoles/ml) and grade 3 (55.8 ؎ 29.2 nmoles/ml) OA. The C6S:C4S ratio was highest in lesions with mild articular changes and reflected the macroscopic alteration of cartilage overlying the ON lesion. The concentration of C6S in the 9 knees with lesions that covered >40% of the condyle (99.0 ؎ 32.9 nmoles/ml) was higher than that in the 17 knees with lesions that covered <40% of the condyle (67.2 ؎ 31.7 nmoles/ml). Knees with bone marrow edema on MRI had a higher level of C6S than did knees with a fibrous-like appearance.Conclusion. While radiologic staging was useful for indicating the size of the ON lesion, it was less valuable for determining articular cartilage damage. Joint fluid analysis may provide more precise information about articular cartilage degradation in ON, and the findings may also be of prognostic significance.

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“…This helps to confir m the specific diagnosis of spontaneous osteonecrosis of the knee. 4 It also plays an important role in patients with symptoms but has a 'normal' plain radiograph. In the case of a torn meniscus, there is no increased activity on the bone scan.…”

Section: Discussionmentioning

confidence: 99%

Acute Non‐Traumatic Knee Pain in the Elderly ‐ Osteoarthritis?

Tan

Ong

Cocks

2000

Hong Kong j. emerg. med.

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We describe a patient with spontaneous osteonecrosis of the knee presenting with acute knee pain. This condition is less often thought of especially among elderly patients who present with knee pain and with no accompanying history of trauma. They are often assumed to be suffering from osteoarthritis. However, we believe that radionuclide bone scan is helpful especially when the plain radiographs are of little or no diagnostic value.

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Radionuclide evaluation of spontaneous femoral osteonecrosis.

Cited by 50 publications

References 0 publications

The Condyle View

The Condyle View

Use of joint fluid analysis for determining cartilage damage in osteonecrosis of the knee

Acute Non‐Traumatic Knee Pain in the Elderly ‐ Osteoarthritis?

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