Radiology–Pathology Conference: sclerosing hemangioma of the lung

Neuman, Jeremy; Rosioreanu, Alex; Schuss, Allan; Turi, George K.; Yung, Elizabeth; Trow, Terence K.; Williams, Lewis E.; Katz, Douglas S.

doi:10.1016/j.clinimag.2006.05.030

Cited by 28 publications

(30 citation statements)

References 15 publications

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“…PSH is usually a solitary, well-circumscribed nodule. Calcification is seldom seen, cystic formation is rare (although it does occur), and cavitation does not occur (8). There is a typical sign in PSHs, which is termed the 'air meniscus sign': This is a lucent zone surrounding PSHs of the lung on plain films (9).…”

Section: Discussionmentioning

confidence: 99%

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Pulmonary sclerosing hemangioma with a rare symptom: A case report and review of the literature

Zhou

Sun

Huang

et al. 2016

Molecular and Clinical Oncology

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Abstract. Pulmonary sclerosing hemangioma (PSH) is a relatively rare benign tumor. However, as it occurs only rarely, the natural course of the tumor is not well understood. In the present study, a case is presented of a 35-year-old woman who underwent intermittent fevers for more than one year. This case highlighted fever as a rare symptom of PSH. Fever is possibly one of the symptoms of PSH, although it is less likely to occur. Another symptom of the patient was that the tumor grew quickly in two months. The lesion was diagnosed as multiple sclerosing hemangioma of the lung (i.e., PSH), in which papillary, solid and sclerotic patterns appeared. Immunohistochemical evaluation of the lesion revealed positive staining for thyroid transcription factor 1 (TTF1), epithelial membrane antigen (EMA), pancytokeratin (PCK) and cytoskeleton 7 (CK7). In the present case study, the biological activity of PSH was identified to be aggressive. A review of the literature was performed in order to comment further on the clinical and pathological features of this rare disease.

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Section: Discussionmentioning

confidence: 99%

“…More recent studies (8,11) have offered a variety of proposed etiologies regarding the cell line of origin, including mesothelial, mesenchymal and neuroendocrine. However, in the present case study, CD56, Syn and CgA were all negative.…”

Section: Discussionmentioning

confidence: 99%

Pulmonary sclerosing hemangioma with a rare symptom: A case report and review of the literature

Zhou

Sun

Huang

et al. 2016

Molecular and Clinical Oncology

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“…As of 2008, there were 10 reported patients with lymph node metastases; in a report with the largest series of nodal metastases, who all underwent lobectomy and regional lymph node dissection (hilar and peribronchial), all four were alive at a mean follow-up of 4.7 years, without evidence of residual or recurrent disease [4,5]. Devouassoux-Shisheboran et al observed several unusual presentations of SH, which included multifocal lesions, hilar lymph nodes, and pleural and mediastinal locations [6].…”

Section: Discussionmentioning

confidence: 99%

“…More recent studies have offered a variety of proposed etiologies regarding the cell line of origin. These include mesothelial, mesenchymal, neuroendocrine and epithelial origins [3,5]. Various diagnostic modalities including immunohistochemistry and electron microscopy have been developed, and this disease is now accepted as an epithelial neoplasm derived from primitive respiratory epithelium, incompletely differentiated type II pneumocytes, or clara cells [6,8].…”

Section: Discussionmentioning

confidence: 99%

“…A thin fibrous pseudocapsule separates it from the surrounding pulmonary paranchyme. Microscopically, SH is composed of two types of cells: cuboidal cells that line papillary structures and round to polygonal cells that form solid sheets [5][6][7]9]. The neoplasm has four possible histologic components: papillary, sclerotic, solid, and hemorrhagic ( Figure 3).…”

Section: Discussionmentioning

confidence: 99%

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Pulmonary sclerosing hemangioma with atypical radiologic findings

et al. 2010

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AbstractSclerosing hemangioma of the lung is an uncommon benign tumour that usually presents as an asymptomatic solitary nodule and affects middle age women. Because there are few findings on radiologic studies that are characteristic of sclerosing hemangioma, it is difficult to diagnose on the basis of imaging and biopsy remains the definitive diagnostic test. We report a case of pulmonary sclerosing hemangioma with extremely unexpected imaging findings and review the literature.

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Benign Epithelial Tumors of the Lung

Weissferdt

2020

Diagnostic Thoracic Pathology

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Radiology–Pathology Conference: sclerosing hemangioma of the lung

Cited by 28 publications

References 15 publications

Pulmonary sclerosing hemangioma with a rare symptom: A case report and review of the literature

Pulmonary sclerosing hemangioma with a rare symptom: A case report and review of the literature

Pulmonary sclerosing hemangioma with atypical radiologic findings

Benign Epithelial Tumors of the Lung

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