Radiology–Pathology Conference

Sex cord-stromal tumors of the ovary: a comprehensive review and update for radiologists

“…GCTs differ from epithelial ovarian neoplasms via predominant unilaterality and confinement to the ovary with no peritoneal seeding at the time of the diagnosis in most cases (3,31). Moreover, GCTs usually do not feature intracystic papillary projections and rarely contain intratumoral calcifications (13,31,38).…”

“…The imaging appearances of these tumors vary according to the gross pathologic tumor characteristics. US and CT imaging usually reveal multicystic masses with solid components and either irregular thickened or thin septations (38) (Fig. 9).…”

“…8). On T2-weighted images, the solid tumor component is usually isointense but thickened septations may be hypointense (15,38). The cystic portions may exhibit fluid-fluid levels and areas of intracystic hemorrhage are typically hyperintense on T1-weighted images (15,38).…”

“…Still, the disease stage at presentation has been shown to be the most important factor (40). Most juvenile GCT cases present with stage I disease and are less likely to recur after simple resection; however, the occasional clinically malignant tumors usually exhibit fast growth and early intra-abdominal spread (13,38).…”

An Unusual Case of Juvenile Granulosa Cell Tumor of the Ovary

“…Granulosa cell tumors are rare sex cord stromal tumors, encompassing 1–5% of all ovarian tumors [1, 2, 3, 4, 5, 6, 7, 8, 9, 10]. These tumors are divided into juvenile and adult types, reflecting not only the typical age of presentation, the differentiating histologic characteristics but also the differing natural history [1, 2].…”