“…49,50 Factors that predispose to pacemaker lead-induced superior vena cava syndrome include the presence of a severed yet retained functionless lead 20,49,51,52 and evidence of infection of the pacemaker generator and lead system. 15,33,35,36,46,49 Clinically, pacemaker lead-induced superior vena cava syndrome is characterized by edema of the face, neck, and upper extremities in conjunction with cyanosis, headache, impaired vision, conjunctival injection, and tautly distended fundal veins. Pulmonary embolization in association with pacemaker lead-induced superior vena cava syndrome is extremely rare but has been detected.i-" DIAGNOSIS Pacemaker lead-induced venous thrombosis may often be diagnosed on the basis of the history and the physical examination.…”