Radiologist Interpretive Volume and Breast Cancer Screening Accuracy in a Canadian Organized Screening Program

Théberge, Isabelle; Chang, Sue-Ling; Vandal, Nathalie; Daigle, Jean-Marc; Guertin, Marie-Hélène; Pelletier, Éric; Brisson, Jacques

doi:10.1093/jnci/djt461

Cited by 28 publications

(32 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Also, sensitivity of approximately 86% was achieved. The results obtained here were more accurate than those reported by Corino et al (64%) (6) .…”

Section: Discussionsupporting

confidence: 80%

“…The usual methods for detection of breast cancer after physical examination are mammography; which is gold standard, magnetic resonance imaging (MRI) and ultrasound (3,4) . Since detection of dense breasts is dif*icult in mammography (5) , the radiographer and also the physician should be pro*icient (6) . The sensitivity for mammography is about 70 percent, and for de*inite diagnosis of cancer there is a need of pathology and biopsy con*irmation.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Detection of breast cancer using non-invasive X-ray diffraction technique of hair: A preliminary study

Maziar¹,

Shahbazi‐Gahrouei²,

Tavakoli³

et al. 2016

IJRR

View full text Add to dashboard Cite

Background: An early diagnosis of breast cancer relates directly to an accurate treatment plan and strategy. Early detec on of breast cancer before its development would be a significant reduc on of morbidity and mortality rates. The aim of this preliminary study is to inves gate the sensi vity of Wide Angle X-ray diffrac on (WAXRD) method on women hair samples of healthy and breast cancer pa ents in comparison with other modali es such as synchrotron based XRD beam and mammography. Materials and Methods: Hair samples were taken from occipital region of skull from healthy and breast cancer pa ents (43 women) were analyzed using X-ray diffrac on and the results were analyzed and compared with mammography and pathology reports. Results: The results of analyzed samples showed the sensi vity for purposed WAXRD method was 86% in comparison with synchrotron based XRD beam (64%) and also with mammography (70%). Conclusion: This non-invasive method is less harmful and is more sensi ve than the two other methods and help the physicians for choosing accurate treatment plan.

show abstract

“…Also, sensitivity of approximately 86% was achieved. The results obtained here were more accurate than those reported by Corino et al (64%) (6) .…”

Section: Discussionsupporting

confidence: 80%

Section: Introductionmentioning

confidence: 99%

Detection of breast cancer using non-invasive X-ray diffraction technique of hair: A preliminary study

Maziar¹,

Shahbazi‐Gahrouei²,

Tavakoli³

et al. 2016

IJRR

View full text Add to dashboard Cite

show abstract

“…Another contributing factor to the quality of reading could be reading volume; a high volume has been shown to reduce radiologists’ false positive rate 24 25. While the average reading volume in Screen Test was about 2300 screening mammograms per year, the minimum requirement for radiologists in the community was 400 mammograms per year during the study period, in accordance with the Canadian Association of Radiologists Mammography Accreditation Program 26…”

Section: Discussionmentioning

confidence: 83%

“…Additionally, the low cancer detection rate was attributed to the lower invasive cancer rate (online supplementary table 4). There are likely variations between different community clinics and individual radiologists,24 25 27 however, we only have aggregated data, so cannot identify individual performance.…”

Section: Discussionmentioning

confidence: 99%

Importance of quality in breast cancer screening practice – a natural experiment in Alberta, Canada

Yuan

Shen

et al. 2020

BMJ Open

View full text Add to dashboard Cite

ObjectivesRegular breast cancer screening is a widely used cancer prevention strategy. Important quality indicators of screening include cancer detection rate, false positive rate, benign biopsy rate and post-screen invasive cancer rate. We compared quality indicators of community radiology clinics to those of ‘Screen Test’, which feature centralised batch reading and quality control processes. Both types of providers operated under a single provincial Breast Cancer Screening Programme.SettingCommunity radiology clinics are operated by independent fee-for-service radiologists serving large and small communities throughout the Canadian province of Alberta. Launched by the provincial cancer agency, the Screen Test operates two physical clinics serving metropolises and mobile units serving remote regions. Eligible women may self-refer to any provider for screening mammography.ParticipantsWomen aged 50 to 69 years who had at least one screening mammogram between July 2006 and June 2010 in Alberta were included. Women with missing health region information or prior breast cancer diagnosis were excluded.ResultsA total of 389 788 screening mammograms were analysed, of which 12.7% were performed by Screen Test. Compared with Screen Test during 2006 to 2008, community radiology clinics had a lower cancer detection rate (3.6 vs 4.6 per 1000 screens, risk ratio (RR): 0.81, 95% CI: 0.67 to 0.98) and a much higher false positive rate (9.4% vs 3.4%, RR: 2.72, 95% CI: 2.55 to 2.90). Most other performance indicators were also better in Screen Test overall and across all health regions. These performance indicators were similar during 2008 to 2010, showing no improvement with time.ConclusionsScreen Test has a quality assurance process in place and performed significantly better. This provides empirical evidence of the effectiveness of a quality assurance process and may explain some of the large differences in breast cancer screening indicators between provinces and countries with formal programmes and those without.

show abstract

“…On the other hand, there is no evidence that more frequent mammography screening or screening with other modalities actually reduces the risk of BC mortality in women with an intermediate or low BC risk (including women with extremely dense breast at mammography) [64]. In addition, mammographic screening has several weaknesses: (a) the risk of false positives; (b) the risk of false negatives; (c) X-ray radiation exposition may trigger BC in high-risk women; (d) mammography performance is operator dependent [65][66][67].…”

Section: High-risk Womenmentioning

confidence: 99%

Why the Gold Standard Approach by Mammography Demands Extension by Multiomics? Application of Liquid Biopsy miRNA Profiles to Breast Cancer Disease Management

Žúbor

Kubatka

Kajo

et al. 2019

IJMS

View full text Add to dashboard Cite

In the global context, the epidemic of breast cancer (BC) is evident for the early 21st century. Evidence shows that national mammography screening programs have sufficiently reduced BC related mortality. Therefore, the great utility of the mammography-based screening is not an issue. However, both false positive and false negative BC diagnosis, excessive biopsies, and irradiation linked to mammography application, as well as sub-optimal mammography-based screening, such as in the case of high-dense breast tissue in young females, altogether increase awareness among the experts regarding the limitations of mammography-based screening. Severe concerns regarding the mammography as the “golden standard” approach demanding complementary tools to cover the evident deficits led the authors to present innovative strategies, which would sufficiently improve the quality of the BC management and services to the patient. Contextually, this article provides insights into mammography deficits and current clinical data demonstrating the great potential of non-invasive diagnostic tools utilizing circulating miRNA profiles as an adjunct to conventional mammography for the population screening and personalization of BC management.

show abstract

Radiologist Interpretive Volume and Breast Cancer Screening Accuracy in a Canadian Organized Screening Program

Cited by 28 publications

References 21 publications

Detection of breast cancer using non-invasive X-ray diffraction technique of hair: A preliminary study

Detection of breast cancer using non-invasive X-ray diffraction technique of hair: A preliminary study

Importance of quality in breast cancer screening practice – a natural experiment in Alberta, Canada

Why the Gold Standard Approach by Mammography Demands Extension by Multiomics? Application of Liquid Biopsy miRNA Profiles to Breast Cancer Disease Management

Contact Info

Product

Resources

About