Radiological diagnosis in cholangiocarcinoma: Application of computed tomography, magnetic resonance imaging, and positron emission tomography

Ringe, Kristina; Wacker, Frank

doi:10.1016/j.bpg.2015.02.004

Cited by 39 publications

(40 citation statements)

References 74 publications

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“…The majority of lesions demonstrate incomplete peripheral enhancement in the arterial phase that may HepatoBiliary Surg Nutr 2017;6(2):67-78 hbsn.amegroups.com become iso-or hypodense in the portal venous phase (32). The central fibrous stroma enhances most prominently in the delayed phase (39), unless there is abundant central mucin or necrosis.…”

Section: Ctmentioning

confidence: 99%

“…While portal vein invasion has been described in the literature as a rare cause of portal venous hypertension (44), the presence of vascular invasion and tumor thrombus formation most commonly serves as a useful differentiating feature from HCC when the pattern of enhancement is equivocal (43). Vascular encasement or narrowing frequently results in atrophy of the involved hepatic segment (45) with or without associated capsular retraction (39), found in approximately 21% of patients (32).…”

Section: Ctmentioning

confidence: 99%

“…One study demonstrated that tumors which demonstrated delayed enhancement over greater than two-thirds of their volume had increased fibrous stroma and a higher incidence of perineural invasion, which is a poor prognostic maker (32,38,40,41). Ancillary features of mCCA on cross-sectional imaging include capsular retraction, biliary obstruction and hepatolithiasis, satellite nodules, vascular encasement, lobar atrophy, and lymphadenopathy (32). Capsular retraction is an imaging feature originally described on CT that is not only associated with cholangiocarcinomas but a variety of other malignant hepatic tumors.…”

Section: Ctmentioning

confidence: 99%

“…18F-Fluoro-2-deoxy-D-glucose (FDG) integrated positron emission tomography (PET) is a non-invasive imaging technique that allows in vivo assessment of the metabolic processes underlying malignant disease (32). Cancer cells are hypermetabolic, a fact which PET imaging exploits for imaging purposes.…”

Section: Pet Imagingmentioning

confidence: 99%

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Multimodality imaging of intrahepatic cholangiocarcinoma

Fábrega-Foster¹,

Ghasabeh²,

Pawlik³

et al. 2017

Hepatobiliary Surg. Nutr.

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Intrahepatic cholangiocarcinomas account for approximately 20% of cases of cholangiocarcinomas.Three growth patterns or morphologic subtypes exist, including mass-forming, periductal-infiltrating, and intraductal-growth subtypes. Knowledge of these morphologic subtypes and their radiologic appearance aids in timely diagnosis, a key to optimizing patient outcomes. The morphologic variability of intrahepatic cholangiocarcinomas has a direct impact on the diagnostic sensitivity and specificity of various diagnostic imaging modalities, including ultrasound (US), computed tomography (CT), magnetic resonance imaging (MRI)/magnetic resonance cholangiopancreatography (MRCP), and positron emission tomography (PET).The following review emphasizes optimal imaging technique for each of these modalities and reviews the imaging appearance of each morphologic subtype of intrahepatic cholangiocarcinoma.

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Section: Ctmentioning

confidence: 99%

Section: Ctmentioning

confidence: 99%

Section: Ctmentioning

confidence: 99%

Section: Pet Imagingmentioning

confidence: 99%

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Multimodality imaging of intrahepatic cholangiocarcinoma

Fábrega-Foster¹,

Ghasabeh²,

Pawlik³

et al. 2017

Hepatobiliary Surg. Nutr.

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“…MRCP can accurately stage CC (81%-96%), with tendency to underestimate ductal involvement. 40 Common imaging characteristics of ICC and PCC are shown in Table 2.…”

Section: Diagnosis Of Cholangiocarcinoma Radiological Diagnosismentioning

confidence: 99%

Comprehensive management of cholangiocarcinoma: Part I. Diagnosis

Papafragkakis

Lee

2017

Int J Gastrointest Interv

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A B S T R A C TCholangiocarcinoma is the second most common primary hepatic malignancy and its incidence is increasing worldwide. Classification and staging of intrahepatic, perihilar, and distal cholangiocarcinomas provide useful prognostic information and further guide in their management. Establishing diagnosis is frequently challenging and may require a multi-modality approach that includes advanced radiological imaging studies and procedures for tissue acquisition; the endoscopic procedures that have been utilized in the management of cholangiocarcinoma comprise endoscopic retrograde cholangiopancreatography with brushing and biopsy, endoscopic ultrasound-guided fine needle aspiration, cholangioscopy with targeted biopsy, and intraductal confocal endomicroscopy. In this review, we will examine the strengths and limitations of each diagnostic tool and assess the serum and bile tumor markers.

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The value of an MRI‐based radiomics model in predicting the survival and prognosis of patients with extrahepatic cholangiocarcinoma

Wang,

Liu,

Zeng

et al. 2024

Cancer Medicine

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ObjectivesThe study aimed to establish radiomics models based on magnetic resonance imaging (MRI) multiparameter images to predict the survival and prognosis of patients with extrahepatic cholangiocarcinoma (ECC).MethodsSeventy‐eight patients with ECC confirmed by pathology were collected retrospectively. The radiomics model_a/b/c were constructed based on the 1/2/3‐year survival of patients with ECC. The best texture features were selected according to postoperative survival time and ECC patient status to calculate the radiomics score (Rad‐score). A cutoff value was selected, and patients were divided into high‐risk and low‐risk groups.ResultsModel_a, model_b, and model_c were used to predict 1‐, 2‐, and 3‐year postoperative survival rates, respectively. The area under the curve values in the training and test groups were 1.000 and 0.933 for model_a, 0.909 and 0.907 for model_b, 1.000 and 0.975 for model_c, respectively. The survival prediction model based on the Rad‐score showed that the postoperative mortality risk differed significantly between risk groups (p < 0.0001).ConclusionsThe MRI radiomics model could be used to predict the survival and prognosis of patients with ECC.

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Radiological diagnosis in cholangiocarcinoma: Application of computed tomography, magnetic resonance imaging, and positron emission tomography

Cited by 39 publications

References 74 publications

Multimodality imaging of intrahepatic cholangiocarcinoma

Multimodality imaging of intrahepatic cholangiocarcinoma

Comprehensive management of cholangiocarcinoma: Part I. Diagnosis

The value of an MRI‐based radiomics model in predicting the survival and prognosis of patients with extrahepatic cholangiocarcinoma

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