Radiological and Pathological Findings in Partial Nephrectomy for Renal Masses : Experience at King Hussein Medical Center

Abstract

Objective:The aim of this study is to assess the accuracy of radiologic findings of renal masses by comparing them with the histopathologic diagnoses from our personal experience in partial nephrectomy specimens. Methods:We reviewed the histopathological reports of 49 patients who underwent partial nephrectomy in a 10 year duration at Prince Hussein bin Abdullah urology and organ transplant centre Results: Only 32 patients of 49 harbored renal cell carcinoma in their specimens with a percentage of 65.4%. The remaining 15 patients had benign renal conditions in a percentage of 30.6%Conclusion: Partial nephrectomy is gold standard for small renal masses, which lead to preserve renal tissue and decrease morbidity and mortality from chronic kidney disease knowing that not all masses proved to be renal cell carcinoma. Despite the fact that renal CT-Scan with IV contrast is considered as the modality of choice for the diagnosis of renal tumors still there is a false positive rate although low but exist.

Correlation between radiological and histopathological findings in patients undergoing nephrectomy for presumed renal cell carcinoma on computed tomography scan at Grey’s Hospital

“…In contrast, Alkaabnah et al reported a higher benign rate of 30% in patients undergoing partial nephrectomy. 12 Nakashima et al attributed a low benign incidence rate of 6.63% in their study to the use of magnetic resonance imaging (MRI) in conjunction with CT scan in their patients, as MRI is known to be more sensitive in detecting small amounts of intralesional fat. 8…”

“…8,9,10,11,16 Ethnicity may predict the type of benign tumours found at nephrectomy performed for presumed RCC, with most Asian studies reporting angiomyolipoma as the most common benign tumour and studies from the US reporting oncocytoma. 2,8,10,11,12 Oncocytoma cannot be confidently distinguished from RCC on imaging. 11,16 We expected that given the high burden of infectious diseases in South Africa, we would see more inflammatory lesions such as xanthogranulomatous pyelonephritis, tuberculosis and aspergillosis being mistaken for RCC.…”