Radiographic and endoscopic regression of metastatic gastric cancer to the colon in the setting of 5-aminosalicylic acid use

Abstract

Colonic metastases from gastric cancer are a rare phenomenon and sparsely reported in the literature. We report a case of a 59-year-old woman who presented with vague abdominal symptoms and initial computer tomography (CT) imaging suggestive of a colonic apple-core lesion with serial colonoscopic biopsies diagnostic of metastatic signet ring cell gastric adenocarcinoma. This case is unique given the evolving CT and endoscopic findings that suggested a regression in colonic wall thickening in the setting of 5-aminosalicylic acid (5-ASA) use prior to histologic diagnosis.

A rare case of colorectal metastasis found 8 years and 10 months after gastrectomy for advanced gastric cancer: A case report and literature review

“…To investigate the characteristics of colon metastasis from gastric cancer, we summarized the reported cases of gastric cancer colon metastasis. Synchronous colorectal metastases differ from metachronous; we found 24 metachronous (1-4,6,14-29) (Table I) and 13 synchronous cases (5,25,(30)(31)(32)(33)(34)(35)(36)(37)(38)(39)(40), as classified and listed in Table II. Several reports have set the boundary between synchronous and metachronous metastases as diagnosed after 2 months, 6 months, and 1 year from the primary diagnosis.…”