Radiofrequency-based carotid wall tracking

Palombo, Carlo; Kozàkovà, M.; Guraschi, N.; Bini, G; Cesana, Francesca; Castoldi, Giovanna; Stella, Andréa; Morizzo, C.; Giannattasio, Cristina

doi:10.1097/hjh.0b013e328354dd44

Cited by 32 publications

(13 citation statements)

References 21 publications

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“…Carotid ultrasound was performed by a single operator (CM) on the right common carotid artery using an ultrasound scanner equipped with a 10 MHz linear probe (MyLab 70, Esaote, Genova, Italy) and implemented with a previously validated radiofrequency-based tracking of arterial wall that allows a real-time determination of common carotid distension (QAS ® ) with high spatial and temporal resolution (sampling rate of 550 Hz on 32 lines) [29]. From the distension curves, one-point carotid PWV (ccaPWV) was calculated applying the Bramwell-Hill equation that relates the propagation velocity to arterial distensibility [30].…”

Section: Methodsmentioning

confidence: 99%

“…The peripheral BP needed for rescaling carotid waveforms was measured at the left brachial artery (Omron, Kyoto, Japan) during each acquisition of the distension curves. Local carotid pressure estimate by QAS was previously validated against applanation tonometry [29] and was used as a surrogate of central aortic pressure.…”

Section: Methodsmentioning

confidence: 99%

“…In our laboratory intra-individual variability of common carotid artery distension by QAS was 7.5 ± 4.6% [29]. …”

Section: Methodsmentioning

confidence: 99%

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Impact of glycemic control on aortic stiffness, left ventricular mass and diastolic longitudinal function in type 2 diabetes mellitus

Kozàkovà

Morizzo

Fraser

et al. 2017

Cardiovasc Diabetol

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BackgroundPoor glycemic control is associated with impaired left ventricular (LV) diastolic function in patients with type 2 diabetes mellitus (T2DM). Inappropriate LV mass increase and accelerated aortic stiffening were suggested to participate on deterioration of diastolic function. The present study investigated the inter-relationships between glycemic control, early diastolic and systolic longitudinal velocity of mitral annulus, LV mass and aortic stiffness in T2DM patients free of cardiovascular disease and with preserved LV ejection fraction, and compared them with those observed in healthy volunteers of similar age and sex distribution.Methods125 T2DM patients and 101 healthy volunteers underwent noninvasive measurement of systolic (s′) and early diastolic (e′) velocities of mitral annulus, LV mass, carotid-femoral pulse wave velocity (cfPWV) and local carotid blood pressure (BP).ResultsForty-four (35.2%) T2DM patients had e′ velocity lower than that expected for age (against 7.9% in healthy volunteers; P < 0.0001), 34 (27.2%) had cfPWV higher than that expected for age and mean BP (against 5.9% in healthy volunteers; P < 0.0001), and 71 (56.8%) had LV mass higher than that expected for body size and stroke work (against 17.6% in healthy volunteers; P < 0.0001). Carotid systolic BP was higher in T2DM patients (124 ± 14 vs 111 ± 11 mmHg; P < 0.0001). In multivariate analysis, e′ velocity was independently related to age, carotid BP and s′ velocity in healthy volunteers, and to male sex, age, carotid BP, heart rate and LV mass in T2DM. Glycosylated hemoglobin (HbA1c) was independently related to cfPWV and LV mass in T2DM patients. T2DM patients with HbA1c ≥6.5% (N = 85) had higher cfPWV (P < 0.05), central BP (P = 0.01), prevalence of LV hypertrophy (P = 0.01) and lower e′ and s′ velocity (P = 0.001 and <0.05, respectively) as compared to those with HbA1c <6.5%.ConclusionsOne-third of T2DM patients with preserved LV ejection fraction has sign of subclinical LV diastolic dysfunction. HbA1c levels are positively associated with LV mass and aortic stiffness, both of which show a negative independent impact on early diastolic velocity e′, the latter through an increase in afterload. T2DM patients with suboptimal glycemic control (HbA1c ≥ 6.5%) have lower diastolic and systolic LV longitudinal performance, together with increased aortic stiffness and a higher prevalence of LV hypertrophy.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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Impact of glycemic control on aortic stiffness, left ventricular mass and diastolic longitudinal function in type 2 diabetes mellitus

Kozàkovà

Morizzo

Fraser

et al. 2017

Cardiovasc Diabetol

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“…Measurements of carotid distension were performed by tracking arterial wall movement with adequate spatial and temporal resolution. 16 Longitudinal images of the both CCA, were obtained with linear 10 MHz probe. A rectangular region of interest (ROI) was placed at CCA segment starting approximately 1–2 cm before the carotid bifurcation.…”

Section: Methodsmentioning

confidence: 99%

Familial history of hypertension as a predictor of increased arterial stiffness in normotensive offspring

Youssef

Tebi

Osama

et al. 2017

The Egyptian Heart Journal

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BackgroundIncreased arterial stiffness can be used as a prognostic marker of arterial hypertension. The relationship between arterial stiffness and arterial hypertension seems to be reciprocal.ObjectiveEvaluation of changes of the arterial elastic prosperities in normotensive subjects, with and without parental history of hypertension.Subjects and MethodsOne hundred and ten normotensive individuals, aged 20–30 years, were divided into two groups: group-A (n = 57) and group-B (n = 53) subjects with positive and negative parental history of hypertension, respectively. Systolic, diastolic and pulse pressures were measured using mercury sphygmomanometer. The elastic properties of the ascending aorta and the common carotid arteries were assessed using M-mode echo and B-mode imaging, respectively. Stiffness index of the digital volume pulse (SIDVP) was measured in the right index finger using photoplethysmography.ResultsGroup A subjects showed higher aortic stiffness index (p = 0.002), carotid stiffness index (p = 0.001), carotid pulse wave velocity (p ⩽ 0.001) and stiffness index of digital volume pulse (p = 0.001). Group A subjects showed lower aortic distensibility (p = 0.001), aortic strain (p = 0.004), changes in aortic diameter (p = 0.022), carotid distension (p = 0.026), carotid distensibility coefficient (p ⩽ 0.001) and carotid compliance coefficient (p = 0.002).ConclusionThe aortic and carotid stiffness parameters and SIDVP were higher in normotensive offspring of hypertensive parents. This finding could direct the attention towards the increased cardiovascular risk in this group and thus prompt earlier and tighter prevention of cardiovascular risk factors.

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“…By analyzing RF, it is possible to reach greater independence and greater measurement accuracy as compared to all other available solutions. [740]…”

Section: Noninvasive Vascular Imaging: Conventional Indices and Stiffmentioning

confidence: 99%

Clinical usefulness of cardio-ankle vascular index, local artery carotid stiffness and global longitudinal strain in subjects with cardiovascular risk factors

Bello

Fabiani

Calogero

et al. 2017

J Cardiovasc Echography

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Radiofrequency-based carotid wall tracking

Abstract: The values of carotid distension and stiffness obtained by two different WTS are not interchangeable and cannot be merged into a common database. Calibrated distension curves may provide an acceptable estimate of local carotid pressure.

Cited by 32 publications

References 21 publications

Impact of glycemic control on aortic stiffness, left ventricular mass and diastolic longitudinal function in type 2 diabetes mellitus

Impact of glycemic control on aortic stiffness, left ventricular mass and diastolic longitudinal function in type 2 diabetes mellitus

Familial history of hypertension as a predictor of increased arterial stiffness in normotensive offspring

Clinical usefulness of cardio-ankle vascular index, local artery carotid stiffness and global longitudinal strain in subjects with cardiovascular risk factors

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