Radiocomplexation and bioevaluation of ^99mTc nitrido-piracetam as a model for brain imaging

Abstract

<jats:title>Abstract</jats:title><jats:p>The aim of the work is to radiolabel a piracetam using [</jats:p>

Radioiodination and bioevaluation of rolipram as a tracer for brain imaging: In silico study, molecular modeling and gamma scintigraphy

“…It was shown to be stable in saline for up to 48 hours. By contrast, in serum after 12 hours, the purity dropped to 97.0% and decreased to 85% at 48 hours …”

“…This indicated that the tracer is excreted through urinary pathways. After 30 minutes, the [ 125 I]iodorolipram uptake notably decreased in the blood, bone, spleen, brain, stomach, muscle, heart, lungs, and liver . The uptake of [ 125 I]iodorolipram in brain is 7.6% ID/g at 10 minutes p.i.…”

“…In addition, [ 125 I]iodorolipram (5 μL [3.20 × 10 −3 GBq]) was checked in saline. At time intervals, the stability of [ 125 I]iodorolipram in 2 different media was assayed using TLC or HPLC techniques and counted in a well‐type γ‐scintillation counter …”

Radioiodination of zearalenone and determination of Lactobacillus plantarum effect of on zearalenone organ distribution: In silico study and preclinical evaluation

“…scarification of animals was conducted after certain times (5 min, 15 min, 30 min, 60 min and 2 h) after injection. Organs were collected in addition to (Fresh blood, bone, and muscle tissues) then measured against prepared standard solution of the labeled substrate [ [56] , [57] , [58] , [59] , [60] , [61] , [62] , [63] , [64] , [65] , [66] , [67] , [68] , [69] , [70] , [71] , [72] , [73] , [74] , [75] , [76] , [77] , [78] , [79] , [80] , [81] , [82] , [83] , [84] , [85] , [86] , [87] , [88] , [89] , [90] , [91] , [92] , [93] , [94] , [95] , [96] , [97] , [98] , [99] , [100] ]. The mean percentage of the injected dose was calculated.…”

Radioiodination of balsalazide, bioevaluation, and characterization as a highly selective radiotracer for imaging of ulcerative colitis in mice

“…At time intervals, the stability of [ 125/131 I]iodobalsalazide radiotracer in two different media was assayed using TLC or HPLC techniques and counted in a well-type γ-scintillation counter. [71][72][73][74][75]…”