Radiochemical determination of nuclear data for theory and applications

Qaim, S.M.

doi:10.1007/s10967-010-0460-5

Cited by 37 publications

(6 citation statements)

References 141 publications

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“…Several other reactions have also been investigated [cf . [20][21][22][23][24]. However, due to the high level of the 125 I (T 1/2 = 60.0 d) impurity associated with those processes, the method 124 Te( p, n) 124 I suggested by our group [19], was found to be more suitable.…”

Section: Production Using Low-energy Reactionsmentioning

confidence: 91%

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Development of novel positron emitters for medical applications: nuclear and radiochemical aspects

Qaim¹

2011

Ract

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In molecular imaging, the importance of novel longer lived positron emitters, also termed as non-standard or innovative PET radionuclides, has been constantly increasing, especially because they allow studies on slow metabolic processes and in some cases furnish the possibility of quantification of radiation dose in internal radiotherapy. Considerable efforts have been invested worldwide and about 25 positron emitters have been developed. Those efforts relate to interdisciplinary studies dealing with basic nuclear data, high current charged particle irradiation, efficient radiochemical separation and quality control of the desired radionuclide, and recovery of the enriched target material for reuse. In this review all those aspects are briefly discussed, with particular reference to three radionuclides, namely 64 Cu, 124 I and 86 Y, which are presently in great demand. For each radionuclide several nuclear routes were investigated but the ( p, n) reaction on an enriched target isotope was found to be the best for use at a small-sized cyclotron. Some other positron emitting radionuclides, such as 55 Co, 76 Br, 89 Zr, 82m Rb, 94m Tc, 120 I, etc., were also produced via the low-energy ( p, n), ( p, α) or (d, n) reaction. On the other hand, the production of radionuclides 52 Fe, 73 Se, 83 Sr, etc. using intermediate energy ( p, xn) or (d, xn) reactions needs special consideration, the nuclear data and chemical processing methods being of key importance. In a few special cases, a high intensity 3 He-or α-particle beam could be an added advantage. The production of some potentially interesting positron emitters via generator systems, for example 44 Ti/ 44 Sc, 72 Se/ 72 As and 140 Nd/ 140 Pr is considered. The significance of new generation high power accelerators is briefly discussed.

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Section: Production Using Low-energy Reactionsmentioning

confidence: 91%

“…Furthermore, in several cases, for example 64 Cu and 124 I, extensive comparisons of various production routes have been presented [cf . 8,20]. Detailed evaluations of the data using nuclear model calculations and statistical fitting procedures have also been performed for several radionuclides [cf .…”

Section: Reaction Cross Section Datamentioning

confidence: 99%

Development of novel positron emitters for medical applications: nuclear and radiochemical aspects

Qaim¹

2011

Ract

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“…The number of relevant reactions studied has therefore also been correspondingly large [cf . 26,27]. However, the low-energy ( p, n)-reaction on an enriched target isotope is favoured because it generally leads to a high-purity product.…”

Section: Novel Positron Emittersmentioning

confidence: 99%

The present and future of medical radionuclide production

Qaim

2012

Radiochimica Acta

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100

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Reactor and cyclotron production of medical radionuclides / γ -ray emitters for SPECT / Positron emitters for PET / Corpuscular radiation emitters for internal radiotherapy / Low and intermediate energy nuclear reactions / Radionuclide generators / Future directionsSummary. Medical radionuclide production technology is well established. Both reactors and cyclotrons are utilized for production; the positron emitters, however, are produced exclusively using cyclotrons. A brief survey of the production methods of most commonly used diagnostic and therapeutic radionuclides is given. The emerging radionuclides are considered in more detail. They comprise novel positron emitters and therapeutic radionuclides emitting low-range electrons and α-particles. The possible alternative production routes of a few established radionuclides, like 68 Ga and 99m Tc, are discussed. The status of standardisation of production data of the commonly used as well as of some emerging radionuclides is briefly mentioned. Some notions on anticipated future trends in the production and application of radionuclides are considered.

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“…Ad di tion ally, in med i cine, the high dose rate (HDR) co balt-60 brachytherapy is ben e fi cial for the treat ment of gynecological can cers, i. e., cer vi cal can cer [17]. The cal cu lated and mea sured data for the radionuclide cobalt-60, es pe cially in the pro duc tion of med i cal radionuclides via par ti cle ac cel er a tor [2,7,18] such as di ag nos tic and ra di a tion ther apy, are of no ta ble op er ative im por tance [19].…”

Section: Introductionmentioning

confidence: 99%

Investigation of the production of cobalt-60 via particle accelerator

Artun

2017

NUCL TECH RAD PROT

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De part ment of Phys ics, Bulent Ecevit Uni ver sity, Zonguldak, Tur key Sci en tific pa per http://doi.org/10.2298/NTRP1704327AThe pro duc tion pro cess of co balt-60 was sim u lated by a par ti cle ac cel er a tor in the en ergy range of 5 to 100 MeV, par ti cle beam cur rent of 1 mA, and ir ra di a tion time of 1 hour to perform yield, ac tiv ity of re ac tion, and in te gral yield for charged par ti cle-in duced re ac tions. Based on nu clear re ac tion pro cesses, the ob tained re sults in the pro duc tion pro cess of cobalt-60 were also dis cussed in de tail to de ter mine ap pro pri ate tar get ma te rial, op ti mum energy ranges, and suit able re ac tions.

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Radiochemical determination of nuclear data for theory and applications

Cited by 37 publications

References 141 publications

Development of novel positron emitters for medical applications: nuclear and radiochemical aspects

Development of novel positron emitters for medical applications: nuclear and radiochemical aspects

The present and future of medical radionuclide production

Investigation of the production of cobalt-60 via particle accelerator

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