“…α-L-Fucose plays a big role in a variety of physiological events such as protein stabilization and function, embryologic development, reproduction, blood group recognition, immune modulation, memory and learning 18,19 . Among the nine sugars present in the structure of glycoprotein, fucose can be used reliably and conveniently for the investigations of glycoprotein synthesis and secretion 20 . Fucose studies have shown that serum fucose level increased in many disease, including cancers and their spread, rheumatoid arthritis, diabetes, Leukocyte adhesion type II, and cystic fibrosis, therefore, it can be used as a biomarker in these pathological conditions 11,21 .…”