Radio frequency plasma assisted surface modification of Fe3O4 nanoparticles using polyaniline/polypyrrole for bioimaging and magnetic hyperthermia applications

Abstract

Surface modification of superparamagnetic Fe3O4 nanoparticles using polymers (polyaniline/polypyrrole) was done by radio frequency (r.f.) plasma polymerization technique and characterized by XRD, TEM, TG/DTA and VSM. Surface-passivated Fe3O4 nanoparticles with polymers were having spherical/rod-shaped structures with superparamagnetic properties. Broad visible photoluminescence emission bands were observed at 445 and 580 nm for polyaniline-coated Fe3O4 and at 488 nm for polypyrrole-coated Fe3O4. These samples exhibit good fluorescence emissions with L929 cellular assay and were non-toxic. Magnetic hyperthermia response of Fe3O4 and polymer (polyaniline/polypyrrole)-coated Fe3O4 was evaluated and all the samples exhibit hyperthermia activity in the range of 42–45 °C. Specific loss power (SLP) values of polyaniline and polypyrrole-coated Fe3O4 nanoparticles (5 and 10 mg/ml) exhibit a controlled heat generation with an increase in the magnetic field.

Superparamagnetic iron oxide nanoparticles for magnetic hyperthermia: recent advancements, molecular effects, and future directions in the omics era

“…From the preliminary hyperthermia and cytotoxicity results, it was shown that coated SPIONs have slightly higher saturation magnetisation values and both coatings have a positive effect on the biocompatibility of the SPIONs. 41 Core-shell nanocomposite materials are another "hot topic" for introducing SPIONs to biological fluids. Inorganic compounds such as calcium phosphate, 42 metallic materials such as silver (Ag) and gold (Au), 43 and biocompatible polymers such as PEG can be used in composite structures.…”

“…From the preliminary hyperthermia and cytotoxicity results, it was shown that coated SPIONs have slightly higher saturation magnetisation values and both coatings have a positive effect on the biocompatibility of the SPIONs. 41…”

Programmable Anisotropic Hydrogels with Localized Photothermal/Magnetic Responsive Properties

“…Magnetization measurements showed that MoS 2 /Fe 3 O 4 possess a saturation 4g). [11] The superparamagnetic properties of MoS 2 /Fe 3 O 4 can effectively prevent the agglomeration of nanosheets after the magnetic field is removed.…”

“…HRTEM images (Figure S1b,d , Supporting Information) further revealed the presence of the crystal lattice fringes with a d ‐spacing of 0.250 nm, which can be assigned to the (220) plane of Fe 3 O 4 . [ 11 ] The corresponding AFM images revealed the uniformity of Fe 3 O 4 NPs on the MoS 2 surface (Figure S1f , Supporting Information), and the thickness was increased to 5.0 ± 0.4 nm. Furthermore, X‐ray photoelectron spectroscopy (XPS, Figure S2 , Supporting Information) and X‐ray diffraction (XRD, Figure S3 , Supporting Information) also confirm the successful synthesis of MoS 2 /Fe 3 O 4 .…”

“…Magnetization measurements showed that MoS 2 /Fe 3 O 4 possess a saturation magnetization of 47.6 emu g −1 , indicating a super‐paramagnetic ability of these MoS 2 /Fe 3 O 4 at room temperature thanks to the efficient modification of Fe 3 O 4 NPs (Figure 4g ). [ 11 ] The super‐paramagnetic properties of MoS 2 /Fe 3 O 4 can effectively prevent the agglomeration of nanosheets after the magnetic field is removed.…”