Radicals scavenging potentials and mosquito vectors’ bio-control measures from bioactive principles of the marine red algae Porteria hornemannii

Abstract

This study investigated the presence of phytochemicals, yield of extract, total phenol and flavonoids content of the red seaweed Porteria hornemannii. For the extraction of metabolites from P. hornemannii, two different solvents like methanol and chloroform were used. In the phytochemical test, the methanol extract of P. hornemannii (MEPH) showed superior results in comparison with chloroform. After the crude methanol extract is purified by 86%, it is subjected to a quantitative method which, respectively, determined the total phenol content to be (1.60 ± 0.13 mg.GAE/g) and flavonoid content to be (1.302 ± 0.4 mg.GAE/g). The GC-MS analyses of MEPH revealed 20 compounds, in which, n-hexadeconic acid (Rt-27.385; peak area − 41.88%) and 9, 12, Octadecadienoic acid (Z, Z) (Rt-29.879; peak area − 19.49%) were the major ones. Based on the concentration of MEPH, both the ABTS and the hydroxyl radical scavenging assays showed increased activity. The larvicidal activity of MEPH tested against three mosquito larvae and found that only Culex quinquefasciatus larvae was highly sensitive (100% mortality) with the LC50 and LC90 value of 2.476 ppm and 13.207 ppm, respectively. Finally, the seaweed P. hornemannii could be considered for the future nutraceutical and bio-control agents, which may also be impervious to cancer and vector-borne diseases in human.

Use of micro and macroalgae extracts for the control of vector mosquitoes

“…stephensi was investigated and larvicidal effects were detected in all extracts applied to all species ( Table 2 ). Furthermore, the methanol extracts were found to have significantly higher toxicity than the chloroform extracts ( Arumugam et al, 2022 ). According to the results of GC-MS analysis of P. hornemannii methanol extract, it was reported that the substance with 41.88% content was n-hexadecanoic acid, which Sigamani et al (2020) showed as the source of high larvicidal effect on mosquito.…”