Use of micro and macroalgae extracts for the control of vector mosquitoes

Abstract

Mosquitoes are one of the most dangerous vectors of human diseases such as malaria, dengue, chikungunya, and Zika virus. Controlling these vectors is a challenging responsibility for public health authorities worldwide. In recent years, the use of products derived from living organisms has emerged as a promising approach for mosquito control. Among these living organisms, algae are of great interest due to their larvicidal properties. Some algal species provide nutritious food for larvae, while others produce allelochemicals that are toxic to mosquito larvae. In this article, we reviewed the existing literature on the larvicidal potential of extracts of micro- and macroalgae, transgenic microalgae, and nanoparticles of algae on mosquitoes and their underlying mechanisms. The results of many publications show that the toxic effects of micro- and macroalgae on mosquitoes vary according to the type of extraction, solvents, mosquito species, exposure time, larval stage, and algal components. A few studies suggest that the components of algae that have toxic effects on mosquitoes show through synergistic interaction between components, inhibition of feeding, damage to gut membrane cells, and inhibition of digestive and detoxification enzymes. In conclusion, algae extracts, transgenic microalgae, and nanoparticles of algae have shown significant larvicidal activity against mosquitoes, making them potential candidates for the development of new mosquito control products.

An oral toxicity assessment of a mosquito larvicidal transgenic algae (Chlamydomonas reinhardtii) using adult Zebrafish and its embryos

“…Some of the deadliest human illnesses, such as Malaria and Dengue fever, have been spread by mosquitoes and have had devastating effects on human populations throughout history [ 5 ]. Many parts of the world are now experiencing the devastating effects of newly emerging mosquito-borne diseases including Zika and Yellow fever [ 6 – 9 ].…”