Radiation sensitivity of 9l gliosarcoma cells at different oxygen pressures

Kapp, John P.; Routh, A; Roden, Susan A.; Deraps, Gordon D.; Barnes, Thomas Y.

doi:10.1016/0090-3019(84)90041-7

Cited by 5 publications

(1 citation statement)

References 12 publications

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“…Although the 9L gliosarcoma cell line has been used frequently in the investigation of PRT,65*67-72 we have used the C6 glioma cell line,a*73*74 because the histological pattern resembles more closely the human glioma and the 9L cell line is a very malignant tumour and resistant to therapy. 75 The C6 glioma rat model is an appropriate size to study the effect of PRT, but uptake studies are more economically performed using a mouse model due to the number of animals required to obtain statistically significant data. There have been difficulties in developing an accu-rate mouse glioma model.…”

Section: Laboratory Investigation Of Prt For Cerebral Tumoursmentioning

confidence: 99%

A Review of Photoradiation Therapy in the Management of Central Nervous System Tumours

Kaye

Hill

1988

Australian and New Zealand Journal of Surgery

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Photoradiation therapy depends on the selective retention of a photosensitizer within the tumour followed by activation of the sensitizer by irradiating the tumour with light of the appropriate wavelength. The present methods of treatment of cerebral glioma are inadequate and the possible benefit of utilizing photoradiation therapy to obtain improved local control of the tumour has been studied in the laboratory and in clinical trials. The biological basis for photoradiation therapy and the laboratory studies and clinical trials involving the use of photoradiation therapy to treat cerebral tumours are discussed.

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Section: Laboratory Investigation Of Prt For Cerebral Tumoursmentioning

confidence: 99%