Abstract:Breast cancer is the most frequent malignancy and the leading cause of cancer morbidity and mortality in women worldwide. Radiation therapy (RT) is a widely used approach for its treatment. About 50% of patients with malignant breast tumors receive radiation therapy and most of them appear to tolerate it, but some experience severe side effects induced by this therapy. This variability of response may be caused by several factors, like age, inflammatory responses, body weight and variation in genes involved in… Show more
“…The sebaceous glands and hair follicles are highly vulnerable to small doses of radiation, leading to the immediate adverse outcomes of alopecia and skin dehydration. [7]…”
Breast cancer is a primary reason for mortality in females, necessitating the creation of innovative and efficient anticancer substances. Recently, about 80% of females identified with breast cancer have turned to specific alternative or supplementary therapies as a viable option for treating their cancer. Botanical extracts have demonstrated potential as anticancer agents with reduced toxicity, excellent safety, and fewer recurring resistance instances than hormonal-targeting anticancer substances. Natural substances commonly act as chemotherapeutic enhancers, antimetastasis, and relieving the toxic and adverse effects caused by anticancer agents. Besides, numerous botanicals enhanced the living standard of individuals with breast cancer. This research focused on clinical experiments and metaanalyses pertaining to the utilization of herbs in the management of breast cancer. This review summarized the majority of the documented clinical investigations concerning the application of ten herbs in the area of breast cancer, including black cohosh, ginseng, ashwagandha, garlic, turmeric, green tea, black seed, flaxseed, guarana, and peppermint. After examining the available research, it seems that the most established medicinal applications of herbal medicine in breast cancer patients involve easing the nausea and vomiting caused by chemotherapy, mitigating the hot flashes caused by hormonal therapy, reducing skin inflammation caused by radiotherapy, alleviating gastrointestinal disorders, and treating mucositis.
“…The sebaceous glands and hair follicles are highly vulnerable to small doses of radiation, leading to the immediate adverse outcomes of alopecia and skin dehydration. [7]…”
Breast cancer is a primary reason for mortality in females, necessitating the creation of innovative and efficient anticancer substances. Recently, about 80% of females identified with breast cancer have turned to specific alternative or supplementary therapies as a viable option for treating their cancer. Botanical extracts have demonstrated potential as anticancer agents with reduced toxicity, excellent safety, and fewer recurring resistance instances than hormonal-targeting anticancer substances. Natural substances commonly act as chemotherapeutic enhancers, antimetastasis, and relieving the toxic and adverse effects caused by anticancer agents. Besides, numerous botanicals enhanced the living standard of individuals with breast cancer. This research focused on clinical experiments and metaanalyses pertaining to the utilization of herbs in the management of breast cancer. This review summarized the majority of the documented clinical investigations concerning the application of ten herbs in the area of breast cancer, including black cohosh, ginseng, ashwagandha, garlic, turmeric, green tea, black seed, flaxseed, guarana, and peppermint. After examining the available research, it seems that the most established medicinal applications of herbal medicine in breast cancer patients involve easing the nausea and vomiting caused by chemotherapy, mitigating the hot flashes caused by hormonal therapy, reducing skin inflammation caused by radiotherapy, alleviating gastrointestinal disorders, and treating mucositis.
“…The risk of radiation using mammography is one of the important disadvantages of using this imaging modality. Younger women are more susceptible to the risk of radiation-induced breast cancer than older women due to their undifferentiated cells being prone to influence by ionizing radiation [5,[10][11][12][13][14][15].…”
Breast cancer is the most common cancer in women. Early diagnosis improves outcome and survival, which is the cornerstone of breast cancer treatment. Thermography has been utilized as a complementary diagnostic technique in breast cancer detection. Artificial intelligence (AI) has the capacity to capture and analyze the entire concealed information in thermography. In this study, we propose a method to potentially detect the immunohistochemical response to breast cancer by finding thermal heterogeneous patterns in the targeted area. In this study for breast cancer screening 208 subjects participated and normal and abnormal (diagnosed by mammography or clinical diagnosis) conditions were analyzed. High-dimensional deep thermomic features were extracted from the ResNet-50 pre-trained model from low-rank thermal matrix approximation using sparse principal component analysis. Then, a sparse deep autoencoder designed and trained for such data decreases the dimensionality to 16 latent space thermomic features. A random forest model was used to classify the participants. The proposed method preserves thermal heterogeneity, which leads to successful classification between normal and abnormal subjects with an accuracy of 78.16% (73.3–81.07%). By non-invasively capturing a thermal map of the entire tumor, the proposed method can assist in screening and diagnosing this malignancy. These thermal signatures may preoperatively stratify the patients for personalized treatment planning and potentially monitor the patients during treatment.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.