Radiation Induced Mucositis: What the Radiologist Needs to Know

Rao, Dinesh; Behzadi, Fardad; Le, Rebecca T.; Dagan, Roi; Fiester, Peter

doi:10.1067/j.cpradiol.2020.10.006

Cited by 14 publications

(9 citation statements)

References 24 publications

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“…The incidence of oral mucositis resulting from RT or chemoradiation in patients with head and neck cancer varies based on the treatment regimen employed, patient-specific characteristics, and the site of the cancer being targeted. Overall, the incidence ranges from 59% to 100%, with severe oral mucositis ranging from 23% to 81% [ 4 , 5 ]. While proton therapy has been associated with a reduction in severe oral mucositis by minimizing integral doses, the incidence of oral mucositis still ranges from 11% to 58% [ 6 , 7 ].…”

Section: Oral Mucositismentioning

confidence: 99%

Oral Complications from Oropharyngeal Cancer Therapy

Sankar,

2023

Cancers

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Post-oropharyngeal cancer treatment complications include a multitude of oral side effects that impact overall survival and quality of life. These include acute and chronic conditions affecting the oral cavity and head and neck, such as mucositis, infection, xerostomia, dysgeusia, radiation caries, osteonecrosis, and trismus. This review will summarize the most common oral complications from oropharyngeal cancer therapy. The authors would like to point out that the literature cited frequently combines oropharyngeal and head and neck cancer results. If recommendations are made strictly related to oropharyngeal cancers, this will be highlighted.

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Section: Oral Mucositismentioning

confidence: 99%

Oral Complications from Oropharyngeal Cancer Therapy

Sankar,

2023

Cancers

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“… 4 , 5 The occurrence of radiation-induced oral mucositis prolongs hospital stays and increases economic burdens, 6 so reducing mucosa injury and improving patient quality of life has always been a focus of radiation therapy doctors. 7 , 8 During radiation therapy, it is recommended to quit smoking tobacco and drinking alcohol, drink plenty of water, and avoid hot, acidic, and spicy foods. Maintaining oral hygiene can also help prevent and reduce radiation oral mucositis.…”

Section: Introductionmentioning

confidence: 99%

Efficacy of Lvpao Powder on Radiation Therapy–Induced Mucositis: A Retrospective Study of 114 Patients With Head and Neck Carcinoma

Chen,

Lu,

Qian

et al. 2024

Advances in Radiation Oncology

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“…On the other hand, the occurrence of radiation-induced oral mucositis prolong hospital stay and increase the economic burdens [6]. So, reducing the mucosa injury and improving the quality of life of patients has always been the focus of radiotherapy doctors [7,8].…”

Section: Introductionmentioning

confidence: 99%

Efficacy of lvpao powder on Radiotherapy-Induced Mucositis: A retrospective study of 11 4 patients with head and neck Carcinoma

Chen

Lü

Qian

et al. 2023

Preprint

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Purpose: To compare the efficacy and safety of kangfuxin solution and lvpao powder on mucositis induced by radiotherapy in head and neck carcinoma patients. Methods: We retrospectively analyzed 114 patients with head and neck malignant tumors in our center. Patients were given Kangfuxin solution to rinse the mouth or Lvpao powder group sprayed the powder on oral mucosa after the solution use. The side effect was evaluated by Common Terminology Criteria for Adverse Events, version 4.0. Results: The grade 3 mucositis occurred in 32.9% (23/70) and 11.4% (5/44) in Kangfuxin solution group and kangfuxin solution plus lvpao powder group respectively(P=0.009). The pain score of the Kangfuxin solution group was significantly higher than that of the Kangfuxin solution and lvpao powder group with 4.26 ± 0.81 vs 3.75 ± 1.03(P=0.007). The time of symptom relief in the combined group was significantly shorter than that in the single drug group with 3 days vs 6 days (P=0.000). The weight loss of the former groups was bigger than that of the latter group(6.67 ± 1.20kg vs 5.95 ± 0.94kg, P=0.001). There was no statistical difference in the limitations in mouth opening(P=0.164). Conclusion: Lvpao powder is safe and effective as a mucosal repair drug in accelerating the recovery of patients and reducing their body weight.

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Radiation Induced Mucositis: What the Radiologist Needs to Know

Cited by 14 publications

References 24 publications

Oral Complications from Oropharyngeal Cancer Therapy

Oral Complications from Oropharyngeal Cancer Therapy

Efficacy of Lvpao Powder on Radiation Therapy–Induced Mucositis: A Retrospective Study of 114 Patients With Head and Neck Carcinoma

Efficacy of lvpao powder on Radiotherapy-Induced Mucositis: A retrospective study of 11 4 patients with head and neck Carcinoma

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