Radiation-induced degradation of carboxymethylated chitosan in aqueous solution

Huang, Ling; Zhai, Maolin; Peng, Jing; Li, Jiuqiang; Wei, Genshuan

doi:10.1016/j.carbpol.2006.05.023

Cited by 52 publications

(21 citation statements)

References 27 publications

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“…There are many reports of the radical-scavenging properties of chitosan and its derivatives [13], but there is some disagreement between the results of different studies. Scavenging of HO • by chitosans of various molecular weights was consistently reported [14,38,39] and is supported by results demonstrating depolymerisation of the polysaccharide chain by HO • [40][41][42][43], although one study led to the unlikely conclusion that sulfated chitosan did not react with this radical [44]. Kinetic measurements have confirmed that the reaction of HO • with carbohydrates is close to diffusion control, with reported rate constants between 1.64 × 10 9 M −1 s −1 for monosaccharides and 1.8 × 10 8 M −1 s −1 for glycogen with 3000 glucose subunits [45][46][47].…”

Section: Discussionsupporting

confidence: 52%

Antioxidant protection of human serum albumin by chitosan

Anraku

Kabashima

Namura

et al. 2008

International Journal of Biological Macromolecules

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Section: Discussionsupporting

confidence: 52%

Antioxidant protection of human serum albumin by chitosan

Anraku

Kabashima

Namura

et al. 2008

International Journal of Biological Macromolecules

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“…2. The increase in the height of the peak at 290 nm could be due to the formation of a carbonyl group in laminarin (Huang, Zhai, Peng, Li, & Wei, 2007;Yoksan, Akashi, Miyata, & Chirachanchai, 2004). The glycosidic bond in laminarin was broken down to carbonyl groups by the hydroxyl radicals generated by gamma irradiation.…”

Section: Uv-vis Absorptionmentioning

confidence: 95%

“…To confirm the carbonyl group formation, Infrared spectra were obtained. The absorption peak at 1630 cm À1 appeared in Fourier transform infrared (FT-IR) spectra of the gamma irradiated laminarin, which was attributed to the absorbance of carbonyl groups (Huang et al, 2007;Tian, Liu, Hu, & Zhao, 2004). The height of this peak was increased at higher dose.…”

Section: Uv-vis Absorptionmentioning

confidence: 98%

Structural feature and antioxidant activity of low molecular weight laminarin degraded by gamma irradiation

Choi¹,

Kim²,

Lee³

2011

Food Chemistry

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“…The broad band between 3420 and 3100 cm -1 due to the -OH stretching vibration is observed. This peak is referred to asymmetry stretching of alcoholic hydroxyl group bonded with water molecule in the hydrogel (32) . On the other hand, curve c shows a band at high wave number appeared at 1638 cm -1 .…”

Section: Timementioning

confidence: 99%

“…Peaks at 1412 cm -1 were assigned to C-O stretch vibration of -COOH. These changes in spectra revealed that although CMCt were cross-linked after irradiation, radiation degradation lead to formation of new carbonyl groups formed and some -NH 2 were scissored out (32) .…”

Section: Timementioning

confidence: 99%

Bio-based Hydrogel Formed by Gamma Irradiation

2016

Egypt. J. Chem.

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ARBOXYMETHYL chitosan (CMCt) was synthesized through ….. carboxymethylation reaction for chitosan. The prepared (CMCt) was subjected to crosslinking reaction by using γ-radiation. Different process parameters were investigated to clarify the effect of radiation dose, pH, and time upon the gel fraction and swelling properties of the produced hydrogels. The gel fraction was reduced after radiation dose 20 KG. The swelling% was dependent on the paste concentrations. At higher paste concentrations, 30-40% higher doses of γ-radiation, 20 KG, were required for optimum swelling. The high concentration paste, 40%, showed superior swelling in alkaline medium, pH > 8, while lower concentration paste manifested optimum swelling in neutral medium, pH = 7. The prepared (CMCt) hydrogels were characterized by FTIR, SEM, DSC and swelling kinetics.Keywords: Carboxymethyl chitosan (CMCt), Hydrogel, γ-ray radiation, Swelling, FTIR, SEM and DSC.Hydrogels are three-dimensional structure of cross-linked polymer, which have affinity for water absorption (1) . The hydrogel matrix has been hold by chemical or physical cross-linking that involves hydrophilic groups of homopolymers or copolymers (2) . Hydrogels swell in water by retaining a significant fraction of water within the pores structure without dissolving (3) . Several applications for hydrogels have been developed in biomedical and industrial fields such as artificial implants, contact lenses, enzyme immobilization (4)(5)(6) . Recent applications for hydrogels are interesting in drug delivery and agriculture in which water release from hydrogel is essential features (7)(8)(9)(10)(11)(12) . Radiation crosslinking is considered as clean and effective method for hydrogel preparation. On comparison with conventional hydrogel preparation, cross-linking through irradiation process did not need initiators, or chemical cross-linking. Radiation methods are efficient and safe alternative for cross-linking without using toxic additives (13) . Lugao reviewed the application of radiation processing in preparing hydrogels (14) . It was shown that the radiation technique is a powerful tool for controlling the degree of cross-linking of the produced hydrogels. Hydrogels, biodegradable and biocompatible polymers, obtained by irradiation cross-linking have a variety of applications, in different fields, such as biomedical devices (15) and control release of drug (16) .

show abstract

Radiation-induced degradation of carboxymethylated chitosan in aqueous solution

Cited by 52 publications

References 27 publications

Antioxidant protection of human serum albumin by chitosan

Antioxidant protection of human serum albumin by chitosan

Structural feature and antioxidant activity of low molecular weight laminarin degraded by gamma irradiation

Bio-based Hydrogel Formed by Gamma Irradiation

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