2014
DOI: 10.1016/j.nano.2014.06.004
|View full text |Cite
|
Sign up to set email alerts
|

Radiation dose enhancement of gadolinium-based AGuIX nanoparticles on HeLa cells

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

0
50
0
1

Year Published

2015
2015
2023
2023

Publication Types

Select...
9
1

Relationship

1
9

Authors

Journals

citations
Cited by 69 publications
(55 citation statements)
references
References 24 publications
0
50
0
1
Order By: Relevance
“…For 50 nm citrate-gold NP, ratio of surviving fractions at 4 Gy were 3.94 and 1.42 for 105 kVp and 6 MeV (Chithrani et al, 2010). For AGuIX NP, Luchette et al gave dose enhancements of 1.54 and 1.15 for 220 kVp and 6 MeV (Luchette et al, 2014). For Hf, the same trend was illustrated by Maggiorella (Maggiorella et al, 2012).…”
Section: Is There An Energy Dependency?mentioning
confidence: 80%
“…For 50 nm citrate-gold NP, ratio of surviving fractions at 4 Gy were 3.94 and 1.42 for 105 kVp and 6 MeV (Chithrani et al, 2010). For AGuIX NP, Luchette et al gave dose enhancements of 1.54 and 1.15 for 220 kVp and 6 MeV (Luchette et al, 2014). For Hf, the same trend was illustrated by Maggiorella (Maggiorella et al, 2012).…”
Section: Is There An Energy Dependency?mentioning
confidence: 80%
“…Nanoparticles such as gadolinium nanoparticles have the potential to improve radiotherapy 82,83 but also provide magnetic resonance imaging (MRI) contrast, which would resonate with recent IGRT developments towards MRI-guided radiotherapy 82,84,85 . The use of nanoparticles with image contrast capability could also facilitate non-invasive monitoring of the effect of radiotherapy and immunotherapy combinations on tumour progression, as shown in recent studies, with nanoparticles designed to allow tracking of cancer-specific T cells in vivo 86,87 .…”
Section: Overcoming Immunosuppressionmentioning
confidence: 99%
“…Interestingly, NPs were designed to serve as radiosensitization enhancers. [14][15][16] Heavy metal (with high-Z elements such as Au, Pt, Bi, Ta, Gd, and Lu 17,18 ) NPs as promising computed tomography (CT) contrast agents (CAs) could be used in radiosensitizing therapy because of their high X-ray photon capture cross-section and compton scattering effect. When X-rays interact with high-Z NPs, Auger electrons and photoelectrons are emitted, with diameters ranging from nanometers to several micrometers.…”
Section: Introductionmentioning
confidence: 99%