Radiation characteristics and implosion dynamics of tungsten wire array Z-pinches on the YANG accelerator

Huang, Xianbin; Yang, Libing; Li, Jing; Zhou, Su-Qin; Ren, Xiaodong; Zhang, Siqun; Dan, Jiakun; Cai, Hongchun; Shuchao, 段书超 Duan; Chen, Guanghua; Zhang, Zhengwei; Ouyang, Kai; Li, Jun; Zhang, Zhaohui; Zhou, Rongguo; Wang, Guilin

doi:10.1088/1674-1056/21/5/055206

Cited by 11 publications

(5 citation statements)

References 21 publications

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“…This, diosgenin has neuroprotective and antioxidant activity, modulates neurotransmitters, is antiapoptotic and anti-inflammatory, attenuates Ca 2+ influx modulating neurotrophic factors, inhibits tau phosphorylation, and can regenerate neural networks (Sun et al, 2015). Some of these activities may well stem from the repression of TNF-α, IL-1β, and IL-6 levels and the NF-κB pathway (Zhang et al, 2017;Man et al, 2023) in addition to the aforementioned actions. Because of these diverse properties, diosgenin can generate mnemonic/ antidepressant/anxiolytic outcomes in our behavioral paradigms following SPS exposure.…”

Section: Discussionmentioning

confidence: 99%

Diosgenin normalization of disrupted behavioral and central neurochemical activity after single prolonged stress

Malik,

Usman,

Arif

et al. 2023

Front. Pharmacol.

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Introduction: Post-traumatic stress disorder (PTSD) is a chronic mental illness triggered by traumatic experiences such as wars, natural disasters, or catastrophes, and it is characterized by anxiety, depression and cognitive impairment. Diosgenin is a steroidal sapogenin with known neuroprotective and antioxidant properties. This study aimed to assess the pharmacological potential of diosgenin in a single prolonged stress (SPS) model of PTSD, plus other behavioral models along with any consequent alterations in brain neurochemistry in male mice.Methodology: SPS was induced by restraining animals for 2 h, followed by 20 min of forced swim, recuperation for 15 min, and finally, exposure to ether to induce anesthesia. The SPS-exposed animals were treated with diosgenin (20, 40, and 60 mg/kg) and compared with the positive controls, fluoxetine or donepezil, then they were observed for any changes in anxiety/depression-like behaviors, and cognitive impairment. After behavioral screening, postmortem serotonin, noradrenaline, dopamine, vitamin C, adenosine and its metabolites inosine and hypoxanthine were quantified in the frontal cortex, hippocampus, and striatum by high-performance liquid chromatography. Additionally, animal serum was screened for changes in corticosterone levels.Results: The results showed that diosgenin reversed anxiety- and depression-like behaviors, and ameliorated cognitive impairment in a dose-dependent manner. Additionally, diosgenin restored monoamine and vitamin C levels dose-dependently and modulated adenosine and its metabolites in the brain regions. Diosgenin also reinstated otherwise increased serum corticosterone levels in SPS mice.Conclusion: The findings suggest that diosgenin may be a potential candidate for improving symptoms of PTSD.

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Section: Discussionmentioning

confidence: 99%

Diosgenin normalization of disrupted behavioral and central neurochemical activity after single prolonged stress

Malik,

Usman,

Arif

et al. 2023

Front. Pharmacol.

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“…For instance, the effect of algae growth and nutrients removal using synthetic wastewater and aerobic granulation in a sequencing batch reactor was investigated 56. In this study, the bioactivity of granules, i.e., nitrifying bacteria, denitrifying bacteria and PAOs (Polyphosphate‐accumulating organisms), decreased due to simultaneous algae growth.…”

Section: Critical Aspects Of Algae Cultivation In Municipal Wastewatermentioning

confidence: 99%

Altered amino acid profile of arbuscular mycorrhizal maize plants under low temperature stress

Zhu

Song

Liu

2016

J. Plant Nutr. Soil Sci.

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We investigated the effect of arbuscular mycorrhiza (AM) on amino acid concentration and composition of maize plants under low‐temperature stress. The AM plants had higher amino acid concentrations than the non‐AM pants. The concentrations of Thr, Lys, Gly, Ala, His, and Ile of the AM plants were higher than non‐AM plants. The results show that low‐temperature stress decreased the concentrations of amino acids and altered their composition.

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“…Compared to QTL localization based on genetic mapping, GWAS and GS have been reported relatively few in sugarcane. For example, GWAS was used for yield (Barreto et al, 2019;Zhang et al, 2023b), sugar content (Racedo et al, 2016;Fickett et al, 2019), fiber composition (Gouy et al, 2015;Yang et al, 2019a), drought tolerance (Wirojsirasak et al, 2023), and disease resistance such as yellow leaf (Debibakas et al, 2014) and orange rust (Yang et al, 2019b); and GS was used for fiber content, flowering (Hayes et al, 2021), yield and sugar (Deomano et al, 2020;Islam et al, 2022), ratooning ability (Islam et al, 2023), and rust resistance (Islam et al, 2021). It should be noted that GS has shown high prediction accuracies in practical breeding programs, and can be a promising tool for improving the rate of genetic gain for quantitative traits in sugarcane breeding (Yadav et al, 2020;Hayes et al, 2021;Islam et al, 2023).…”

Section: Breeding 20mentioning

confidence: 99%

Sugarcane breeding: a fantastic past and promising future driven by technology and methods

Lu,

Liu,

et al. 2024

Front. Plant Sci.

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Sugarcane is the most important sugar and energy crop in the world. During sugarcane breeding, technology is the requirement and methods are the means. As we know, seed is the cornerstone of the development of the sugarcane industry. Over the past century, with the advancement of technology and the expansion of methods, sugarcane breeding has continued to improve, and sugarcane production has realized a leaping growth, providing a large amount of essential sugar and clean energy for the long-term mankind development, especially in the face of the future threats of world population explosion, reduction of available arable land, and various biotic and abiotic stresses. Moreover, due to narrow genetic foundation, serious varietal degradation, lack of breakthrough varieties, as well as long breeding cycle and low probability of gene polymerization, it is particularly important to realize the leapfrog development of sugarcane breeding by seizing the opportunity for the emerging Breeding 4.0, and making full use of modern biotechnology including but not limited to whole genome selection, transgene, gene editing, and synthetic biology, combined with information technology such as remote sensing and deep learning. In view of this, we focus on sugarcane breeding from the perspective of technology and methods, reviewing the main history, pointing out the current status and challenges, and providing a reasonable outlook on the prospects of smart breeding.

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Radiation characteristics and implosion dynamics of tungsten wire array Z-pinches on the YANG accelerator

Cited by 11 publications

References 21 publications

Diosgenin normalization of disrupted behavioral and central neurochemical activity after single prolonged stress

Diosgenin normalization of disrupted behavioral and central neurochemical activity after single prolonged stress

Altered amino acid profile of arbuscular mycorrhizal maize plants under low temperature stress

Sugarcane breeding: a fantastic past and promising future driven by technology and methods

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