Quorum‐quenching enzymes: Promising bioresources and their opportunities and challenges as alternative bacteriostatic agents in food industry

Dangfeng, Wang; Cui, Fangchao; Ren, Likun; Li, Jianrong; Li, Tingting

doi:10.1111/1541-4337.13104

Cited by 4 publications

(2 citation statements)

References 189 publications

(199 reference statements)

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“…Furthermore, AHL amidase irreversibly breaks the amide bond of AHL, producing homoserine lactone. While AHL oxidoreductase can catalyze the oxidation or reduction of AHL, research on this category remains limited. − Despite the existence of various enzymes capable of degrading signal molecules, these enzymes have several drawbacks, including low activity, susceptibility to environmental conditions, and limited specificity. Hence, further screening and modification of QS signal molecule-degrading enzymes are imperative.…”

Section: Qs and Qsismentioning

confidence: 99%

Disruption of Communication: Recent Advances in Antibiofilm Materials with Anti-Quorum Sensing Properties

Qu,

Zou,

Wang

et al. 2024

ACS Appl. Mater. Interfaces

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Biofilm contamination presents a significant threat to public health, the food industry, and aquatic/marine-related applications. In recent decades, although various methods have emerged to combat biofilm contamination, the intricate and persistent nature of biofilms makes complete eradication challenging. Therefore, innovative alternative solutions are imperative for addressing biofilm formation. Instead of solely focusing on the eradication of mature biofilms, strategically advantageous measures involve the delay or prevention of biofilm formation on surfaces. Quorum sensing, a communication system enabling bacteria to coordinate their behavior based on population density, plays a pivotal role in biofilm formation for numerous microbial species. Materials possessing antibiofilm properties that target quorum sensing have gained considerable attention for their potential to prevent biofilm formation. This Review consolidates recent research progress on the utilization of materials with antiquorum sensing properties for combating biofilm formation. These materials can be categorized into three distinct types: (i) antibiofilm nanomaterials, (ii) antibiofilm surfaces, and (iii) antibiofilm hydrogels with antiquorum sensing capabilities. Finally, the Review concludes with a brief discussion of current challenges and outlines potential avenues for future research.

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Section: Qs and Qsismentioning

confidence: 99%

Disruption of Communication: Recent Advances in Antibiofilm Materials with Anti-Quorum Sensing Properties

Qu,

Zou,

Wang

et al. 2024

ACS Appl. Mater. Interfaces

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“…Совокупность таких механизмов получила название «чувство кворума» (Quorum Sensing). Впервые этот термин был введён в 1994 году (Coquant G et al, 2021;Whiteley M et al, 2017;Abisado RG et al, 2018).…”

Section: Introductionunclassified

Antibacterial activity and Quorum quenching mechanisms of the genus Bacillus (review)

Lazebnik,

Kosyan,

Laryushina

2023

AHFP

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https://orcid.org/0000-0001-5571-4535Аннотация. Нарушение деятельности пищеварительного тракта животных и птицы является одной из актуальных проблем сельского хозяйства. Эффективной стратегией лечения и профилактики болезней пищеварительной системы представляется разработка и внедрение в практику ветеринарии новых высокоэффективных пробиотических препаратов. Пробиотики появились как потенциальная альтернатива антибиотикам и общепризнанно считаются безопасными для здоровья организма-хозяина. В основе межклеточной коммуникации, в том числе и между патогенными и пробиотическими бактериями, лежат сложные механизмы регуляции экспрессии генов, зависящие от плотности бактериальной популяции. Совокупность таких механизмов получила название «чувство кворума» (Quorum Sensing). Феномен чувства кворума включает в себя биосинтез и высвобождение сигнальных молекул различной химической структуры (аутоиндукторов), пороговая концентрация которых запускает биологический ответ. В обзоре представлены основные механизмы подавления бактериального чувства кворума и пути практического применения этого феномена в сельском хозяйстве. Одним из таких путей является использование бактериальных штаммов рода Bacillus, которые производят множество антимикробных пептидов, различных по химической структуре. Бактериоцины, продуцируемые штаммами рода Bacillus, можно рассматривать как вторые по значению после бактериоцинов лактобактерий. На основе штаммов бацилл создано большое количество пробиотических препаратов для медицинского и ветеринарного применения.

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Nanotechnology‐driven strategies to enhance the treatment of drug‐resistant bacterial infections

Zhang,

Liu,

Guo

et al. 2024

WIREs Nanomed Nanobiotechnol

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The misuse of antibiotics has led to increased bacterial resistance, posing a global public health crisis and seriously endangering lives. Currently, antibiotic therapy remains the most common approach for treating bacterial infections, but its effectiveness against multidrug‐resistant bacteria is diminishing due to the slow development of new antibiotics and the increase of bacterial drug resistance. Consequently, developing new a\ntimicrobial strategies and improving antibiotic efficacy to combat bacterial infection has become an urgent priority. The emergence of nanotechnology has revolutionized the traditional antibiotic treatment, presenting new opportunities for refractory bacterial infection. Here we comprehensively review the research progress in nanotechnology‐based antimicrobial drug delivery and highlight diverse platforms designed to target different bacterial resistance mechanisms. We also outline the use of nanotechnology in combining antibiotic therapy with other therapeutic modalities to enhance the therapeutic effectiveness of drug‐resistant bacterial infections. These innovative therapeutic strategies have the potential to enhance bacterial susceptibility and overcome bacterial resistance. Finally, the challenges and prospects for the application of nanomaterial‐based antimicrobial strategies in combating bacterial resistance are discussed.This article is categorized under: Biology‐Inspired Nanomaterials > Nucleic Acid‐Based Structures Therapeutic Approaches and Drug Discovery > Nanomedicine for Infectious Disease

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Quorum‐quenching enzymes: Promising bioresources and their opportunities and challenges as alternative bacteriostatic agents in food industry

Cited by 4 publications

References 189 publications

Disruption of Communication: Recent Advances in Antibiofilm Materials with Anti-Quorum Sensing Properties

Disruption of Communication: Recent Advances in Antibiofilm Materials with Anti-Quorum Sensing Properties

Antibacterial activity and Quorum quenching mechanisms of the genus Bacillus (review)

Nanotechnology‐driven strategies to enhance the treatment of drug‐resistant bacterial infections

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