Quinazolinone Sulfonamides as Diuretic Agents

Abstract

Poly-y-benzyl glutamates also exhibit association in solvents such as chloroform and dioxane; P.

Convenient and Scalable Synthesis of 2,3-Dihydroquinazolin-4(1H)-one Derivatives and Their Anticancer Activities

“…2,3-Dihydroquinazolin-4(1H)-one derivatives are an important class of fused Ncontaining heterocycles with various biological, medicinal, and pharmacological activities such as antitumor [3] , antibiotic [4] , antifungal [5] , analgesic [6] , diuretic [7] , antifertility [8] , antidepressant [9] , antihistaminic [10] , vasodilating [11] , and antifibrillatory agent [12] . In addition, these compounds can act as potent tubulin inhibitors with promising anti-proliferative activity against several human cancer cell lines [13] .…”

Synthesis of 2-aryl substituted 2,3-dihydroquinazoline-4(1H)-ones under solvent free conditions using ionic liquid as a mild and efficient catalyst

“…These are widely used in biological and pharmaceutical activities [1]. The quinazolinones display wide range of biological activities such as antitumor [2,3], antidefibrillatory [4], antidepressant [5], analgesic [6], diuretic [7], antihistamine [8], vasodilating [9], antihypertensive [10], CNS stimulant [11], tranquilizing [12] and antianxietic [13]. Some representative drug molecules having quinazoline skeleton are shown in Figure 1.…”

An efficient one‐pot solvent‐free synthesis of 2,3‐dihydroquinazoline‐4(1H)‐ones via Al/Al2O3 nanoparticles

“…Dihydroquinazolinones and their derivatives are important heterocyclic compounds, which influence numerous cellular processes. They are analgesic, diuretic, and vasodilating agents, displaying a broad range of biological, medicinal, and pharmacological properties [1–10]. Also, they are constituents of antitumor, antibiotic, antidefibrillatory, antipyretic, antihypertonic, antihistamine, and antidepressant drugs.…”