QuEChERS Pretreatment Combined with Ultra-performance Liquid Chromatography–Tandem Mass Spectrometry for the Determination of Four Veterinary Drug Residues in Marine Products

Chen, Jian; Wei, Zhen; Cao, Xian Ying

doi:10.1007/s12161-018-01431-1

Cited by 17 publications

(3 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It was observed that the highest SERS intensity for 4−MBA detection was achieved by Au@Ag NRs substrates fabricated using 100 μL AgNO 3 . The volume of AgNO 3 used during the preparation process can affect the aspect ratio, Ag shell thickness and morphology of Au@Ag NRs substrates [ 29 , 30 ]. As shown in the TEM results ( Figure 2 C), homogeneous and equal morphology was obtained when preparing Au@Ag NRs using 100 μL AgNO 3 .…”

Section: Resultsmentioning

confidence: 99%

High-Performance Au@Ag Nanorods Substrate for SERS Detection of Malachite Green in Aquatic Products

Chen

Pan

et al. 2023

Biosensors

View full text Add to dashboard Cite

In order to improve the detection performance of surface-enhanced Raman scattering (SERS), a low-cost Au@Ag nanorods (Au@Ag NRs) substrate with a good SERS enhancement effect was developed and applied to the detection of malachite green (MG) in aquaculture water and crayfish. By comparing the SERS signal enhancement effect of five kinds of Au@Ag NRs substrates with different silver layer thickness on 4-mercaptobenzoic acid (4-MBA) solution, it was found that the substrate prepared with 100 µL AgNO3 had the smallest aspect ratio (3.27) and the thickest Ag layer (4.1 nm). However, it showed a good signal enhancement effect, and achieved a detection of 4-MBA as low as 1 × 10−11 M, which was 8.7 times higher than that of the AuNRs substrate. In addition, the Au@Ag NRs substrate developed in this study was used for SRES detection of MG in crayfish; its detection limit was 1.58 × 10−9 M. The developed Au@Ag NRs sensor had the advantages of stable SERS signal, uniform size and low cost, which provided a new tool for SERS signal enhancement and highly sensitive SERS detection method development.

show abstract

Section: Resultsmentioning

confidence: 99%

High-Performance Au@Ag Nanorods Substrate for SERS Detection of Malachite Green in Aquatic Products

Chen

Pan

et al. 2023

Biosensors

View full text Add to dashboard Cite

show abstract

“…In 2003, Anastassiades et al developed the QuEChERS method to process samples in pesticide residue analysis [25]. QuEChERS was widely used in the pesticide residue extraction process of samples with a high water content, such as fruits and vegetables [26]. Compared with the traditional standard extraction methods, the QuEChERS method has the following advantages: (1) high recovery rate; (2) high precision and accuracy that can be calibrated by internal standard method; (3) a wide range of pesticides that can be analyzed; (4) a fast sample processing speed; (5) the low amount of solvent, the low pollution, and the low price; and (6) the easy experiment operation and simple equipment [24,27,28].…”

Section: Optimization Of Extraction and Purificationmentioning

confidence: 99%

Evaluation of Dissipation Behavior, Residues, and Dietary Risk Assessment of Fludioxonil in Cherry via QuEChERS Using HPLC-MS/MS Technique

Yao¹,

Zhao²,

Wang³

et al. 2021

Molecules

View full text Add to dashboard Cite

The chemical fungicide fludioxonil is widely used to control post-harvest fungal disease in cherries. This study was implemented to investigate the dissipation behaviours and residues of fludioxonil on cherries. A reliable and efficient analytical method was established. Cherry samples from four product areas were analyzed by QuEChERS and HPLC-MS/MS methods with acceptable linearity (R2 > 0.99), accuracy (recoveries of 81–94%), and precision (relative standard deviation of 2.5–11.9%). The limits of quantification (LOQs) and limits of detection (LODs) of cherries were 0.01 mg/kg and 0.005 mg/kg. The dissipation of fludioxonil on cherries followed first order kinetics with half-lives of 33.7–44.7 days. The terminal residues of fludioxonil were all lower than 5.00 mg/kg, which is the MRL recommended by the European Commission. According to Chinese dietary patterns and terminal residue distributions, the risk quotient (RQs) of fludioxonil was 0.61%, revealing that the evaluated cherries exhibited an acceptably low dietary risk to consumers.

show abstract

“…[10] QuEChERS purification was used to determine four kinds of veterinary drug residues in seafood, sulfa, tetracycline, quinolone, and malachite green residues. [11] Enhanced matrix removal of lipids (EMR-Lipid) was utilized to analyze multi-class, multi-residue veterinary drug detection. [12][13][14] A solid-supported liquid extraction clean-up using a diatomaceous earth minicartridge was applied to co-extract seven veterinary drugs in processed chicken food and muscle.…”

Section: Introductionmentioning

confidence: 99%

Optimization of 204 veterinary drug residues method and establishing their mass spectrum library

Fang

et al. 2021

International Journal of Food Properties

View full text Add to dashboard Cite

A multi-class multi-residue analytical method was validated in this paper for simultaneously identifying 204 veterinary drugs in pork by UPLC-QTRAP MS/MS, including sulfonamides, quinolones, β-agonists, and nitroimidazoles. MRM-IDA-EPI mode of QTRAP was used to establish a secondary mass spectrum library of these 204 veterinary drugs, which could enhance the qualitative analysis of suspect substances. The separation of substances was performed on a C18 column, with a gradient elution of 0.1% formic acid solution in water and methanol. Electrospray ionization (ESI), fast polarity switching, and scheduled MRM mode were used to collect the characterization results. Factors that affected the recovery were delicately optimized, such as solvent proportion, formic acid content, and purification method. We finally determined the extracting method with formic acidacetonitrile-water (0.1:90:10, v:v:v) and purifying method with Cleanert LipoNo as a package for dispersive solid-phase extraction. Matrix effects on the quantitative results were also investigated. Some compounds had strong matrix inhibition or enhancement, and the matrix matching external standard method was used to quantify the compounds accurately. The correlation coefficient R 2 was over 0.99 within the calibration linearity range for the detected 204 veterinary drugs. The limit of quantification (LOQ) was 0.5 ~ 5 μg/kg. The recoveries ranged from 61.4% to 118.8% with RSDs of 3.1% to 19.2% (n = 6).

show abstract

QuEChERS Pretreatment Combined with Ultra-performance Liquid Chromatography–Tandem Mass Spectrometry for the Determination of Four Veterinary Drug Residues in Marine Products

Cited by 17 publications

References 26 publications

High-Performance Au@Ag Nanorods Substrate for SERS Detection of Malachite Green in Aquatic Products

High-Performance Au@Ag Nanorods Substrate for SERS Detection of Malachite Green in Aquatic Products

Evaluation of Dissipation Behavior, Residues, and Dietary Risk Assessment of Fludioxonil in Cherry via QuEChERS Using HPLC-MS/MS Technique

Optimization of 204 veterinary drug residues method and establishing their mass spectrum library

Contact Info

Product

Resources

About