Quantum Dot-Based Biosensor for the Detection of Human T-Lymphotropic Virus-1

Norouzi, Mehdi; Ghobadi, Mohadeseh Zarei; Golmimi, Mohammad; Mozhgani, Sayed‐Hamidreza; Ghourchian, Hedayatollah; Rezaee, Seyed Abdolrahim

doi:10.1080/00032719.2017.1287714

Cited by 24 publications

(18 citation statements)

References 38 publications

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“…But these methods, are most frequently used for determining prognosis and progression, rather than for early detection. In contrast, HTLV-1 integrates into the host genomic DNA and produces the latency and consequently escapes from the host immune response, so its early detection is complicated (Dehée et al, 2002;Norouzi et al, 2017).…”

Section: Molecular Methodsmentioning

confidence: 99%

“…Then, the quantum dot solution was added to the sandwich complex conjugated with the amine group of the reporter probe and finally, emission spectra of the quantum dots were recorded. The biosensor response was linear with HTLV-1 concentrations from 10 pg/µl to 0.24 ng/µl, with a detection limit of 19.5 pg/µl ( Figure 3; Norouzi et al, 2017).…”

Section: New Development In Biosensing Research For Htlv-1 Detectionmentioning

confidence: 96%

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Current approaches for detection of human T‐lymphotropic virus Type 1: A systematic review

Fani

Rezayi

Meshkat

et al. 2019

Journal Cellular Physiology

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Background Human T‐lymphotropic virus Type 1 (HTLV‐1) is a retrovirus that is endemic in some regions of the world. It is known to cause several diseases like adult T‐cell leukemia (ATL) and HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP). Serology and molecular methods have been used to detect this virus. Of these, enzyme‐linked immunosorbent assay (ELISA) is used as a primary screening method and this is usually followed by western blotting (WB) and polymerase chain reaction (PCR) methods as confirmatory tests. We conducted a systematic review of the different techniques used in the diagnosis of HTLV‐1 infection. Materials and Methods Our search was limited to original papers in the English language from 2010 to 2018 using several databases including Pubmed, Scopus, Google Scholar, Iranmedex, and Scientific Information Database. A manual search of references provided in the included papers was also performed. Results Of 101 electronically searched citations, 43 met the inclusion criteria. ELISA is commonly used for qualitative and screening detection, and WB and PCR techniques are used to confirm infection. Conclusion Among all the reported methods for detection of HTLV‐1, only serological and molecular tests are used as the most common technical assays for HTLV‐1. The ELISA assay, without a confirmatory test, has several limitations and affect the accuracy of the results. Owing to the prevalence of HTLV‐1 and limitations of the current detection methods, further evaluation of the accuracy of these methods is needed. There are new opportunities for applying novel technological advances in microfluidics, biosensors, and lab‐on‐a‐chip systems to perform HTLV‐1 diagnostics.

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Section: Molecular Methodsmentioning

confidence: 99%

Section: New Development In Biosensing Research For Htlv-1 Detectionmentioning

confidence: 96%

Current approaches for detection of human T‐lymphotropic virus Type 1: A systematic review

Fani

Rezayi

Meshkat

et al. 2019

Journal Cellular Physiology

Self Cite

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“…Norouzi et al developed a cadmium-tellurium QD in association with a biotin acceptor and NH 2 -receptor probes with target DNA for recognition of human T-lymphotropic virus-1 (HTLV-1) in vitro. 97 Likewise, there are many other evaluations where QDs have been utilized either as therapeutics or for in vitro diagnosis of viral pathogens.…”

Section: Quantum Dotsmentioning

confidence: 99%

Nano-based approach to combat emerging viral (NIPAH virus) infection

Kerry

Malik

Redda

et al. 2019

Nanomedicine: Nanotechnology, Biology and Medicine

108

107

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Emergence of new virus and their heterogeneity are growing at an alarming rate. Sudden outburst of Nipah virus (NiV) has raised serious question about their instant management using conventional medication and diagnostic measures. A coherent strategy with versatility and comprehensive perspective to confront the rising distress could perhaps be effectuated by implementation of nanotechnology. But in concurrent to resourceful and precise execution of nano-based medication, there is an ultimate need of concrete understanding of the NIV pathogenesis. Moreover, to amplify the effectiveness of nano-based approach in a conquest against NiV, a list of developed nanosystem with antiviral activity is also a prerequisite. Therefore the present review provides a meticulous cognizance of cellular and molecular pathogenesis of NiV. Conventional as well several nano-based diagnosis experimentations against viruses have been discussed. Lastly, potential efficacy of different forms of nano-based systems as convenient means to shield mankind against NiV has also been introduced.

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“…[82,91] CdTe quantum dots (CdTe QDs) mixed with sandwiched complexes, NH 2 -reporter, and biotin receptor and target DNA accelerating the research for developing a sensor for human T-lymphotropic virus-1 (HTLV-1) identification. [92] Au NPs based materials are well known for the detection of various viruses such as dengue virus, influenza virus, bovine viral diarrhea coronavirus, etc. [93] Recently, Seo et al [94] reported the field-effect transistor (FET) based biosensor for SARS-CoV-2.…”

Section: Case Studiesmentioning

confidence: 99%

COVID‐19: Emergence of Infectious Diseases, Nanotechnology Aspects, Challenges, and Future Perspectives

Gupta

Kumar

et al. 2020

ChemistrySelect

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Wuhan, a city of China, is the epicenter for the pandemic outbreak of coronavirus disease-2019 (COVID-19). It has become a severe public health challenge to the world and established a public health emergency of international worry. This infectious disease has pulled down the economy of almost all top developed nations. The coronaviruses (CoVs) known for various epidemics caused time to time. Infectious diseases such as severe acute respiratory syndrome (SARS) and middle east respiratory syndrome (MERS), followed by COVID-19, are all coronaviruses led outbreaks that scourged the history of mankind. CoVs evolved themselves to more infectious, transmissible, and more pandemic with time. To prevent the spread of the SARS-CoV-2, many countries have ordered the complete lockdown to combat the outbreak. This paper briefly discussed the historical background of CoVs and the evolution of human coronaviruses (HCoVs), the case studies and the development of their antiviral medications. The viral infection encountered with present-day challenges and futuristic approaches with the help of nanotechnology to minimize the spread of infectious viruses. The antiviral drugs and their clinical advances, along with herbal medicines for viral inhibition and immunity boosters, are described. Elaboration of tables related to CoVs for the compilation of the literature has been adopted for the better understanding.

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Quantum Dot-Based Biosensor for the Detection of Human T-Lymphotropic Virus-1

Cited by 24 publications

References 38 publications

Current approaches for detection of human T‐lymphotropic virus Type 1: A systematic review

Current approaches for detection of human T‐lymphotropic virus Type 1: A systematic review

Nano-based approach to combat emerging viral (NIPAH virus) infection

COVID‐19: Emergence of Infectious Diseases, Nanotechnology Aspects, Challenges, and Future Perspectives

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