Quantitative Trait Loci Mapping for Porcine Backfat Thickness

Wu, Xiaolin; Lee, C.; Jiang, Jianhua; Peng, Yong; Yan, Honglang; Yang, S. L.; Xiao, B. N.; Liu, X. C.; Shi, Qiuxiang

doi:10.5713/ajas.2002.932

Cited by 7 publications

(4 citation statements)

References 27 publications

(30 reference statements)

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“…The QTL was located between the marker loci S0062 and S0120. This region concurred with the location of the back-fat thickness QTL that was found in the study by Wu et al (2001Wu et al ( , 2002 and Lee et al (2003). The QTL was in the proximity of the regions where some growth hormone pathway genes are located.…”

Section: Discussionsupporting

confidence: 84%

Genetic Variation and Association of Insulin-Like Growth Factor Binding Protein-3 with Performance in Swine

Wang

Meng

et al. 2009

Biochem Genet

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Genetic variation of insulin-like growth factor binding protein-3 was analyzed in 17 pig breeds (14 native Chinese and 3 European). Using PCR-single strand conformation polymorphism, we found a polymorphism in intron 2, and this SNP was the combined mutation of G897T-G903A-C911T. The Chinese breeds carried a higher TAT/TAT genotype frequency (over 50%), except for Bamei (22%), Yujiang Black (0.0%), and Erhualian (10.0%); the European breeds had a higher GGC/GGC genotype frequency (Large White 1.67%, Landrace 13.89%, Duroc 0.0%). The allelic frequency of TAT in Chinese breeds was over 50%, except for Yujiang Black (12.5%); the allelic frequency of GGC was over 50% in all European breeds. The effect of genotype on 43 performance traits was investigated in one population (Lantang x Landrace). Pigs with the TAT/TAT genotype had higher B-point and C-point back-fat thickness than pigs with the GGC/GGC genotype. The TAT/TAT pigs also scored higher in meat color than the GGC/GGC pigs. These results implied that IGFBP-3 may affect meat quality and carcass traits.

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Section: Discussionsupporting

confidence: 84%

Genetic Variation and Association of Insulin-Like Growth Factor Binding Protein-3 with Performance in Swine

Wang

Meng

et al. 2009

Biochem Genet

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“…It is currently observed that IMF content is positively correlated with subcutaneous fatness. Many experiments have succeeded in identifying chromosome regions associated with backfat thickness (BFT) (Wu et al, 2001(Wu et al, , 2002. In the same studies, chromosome-wise evidence for QTL affecting BFT was found around 53cM, close to marker SW752 (Zuo et al, 2003).…”

Section: Qtl Analysismentioning

confidence: 99%

Mapping Quantitative Trait Loci for Meat Quality on Pig Chromosome 3, 4 and 7

Zuo¹,

Xiong²,

Su³

et al. 2003

Asian Australas. J. Anim. Sci

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The objective of this study was to localize QTL affecting meat quality in a pig family of three generations. All animals were genotyped for twenty-four microsatellites on SSC3 (Sus scrofa chromosome 3), SSC4 and SSC7. One hundred and forty F 2 offsprings were scored for eleven meat quality traits. Least square regression interval mapping revealed quantitative trait loci (QTL) effect for meat pH (m. Semipinalis Capitis, SC) on SSC4 and SSC7; for moisture (m. Longissimus Dorsi, LD) on SSC3. Furthermore, there was suggestive evidence for a QTL on SSC4 affecting intramuscular fat (IMF) content that nearly approached the chromosomewise (p=0.05) significance threshold.

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“…However, in this study, the significant associations of E36 with backfat depth traits were mainly observed in live animals (Table 4). This could have occurred if the region harboring the IFRD1 gene contained other genes that affect carcass backfat traits, such as IGFBP3 (insulin-like growth factor binding protein 3) (Wu et al 2002;Wang et al 2009) and PRKAG2 (protein kinase, AMPactivated, gamma 2 non-catalytic subunit) (Demeure et al 2004). …”

Section: Discussionmentioning

confidence: 98%

Association of eight EST-derived SNPs with carcass and meat quality traits in pigs

et al. 2014

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The identification of genetic markers associated with important economic traits is fundamental to improving the productivity and quality of livestock. In this investigation, we searched for 177 expressed sequence tags (ESTs) putatively involved in meat quality from the available pig EST database, and detected eight single nucleotide polymorphisms (SNPs) in eight ESTs. We investigated the associations of these SNPs with 18 carcass and meat quality traits in a Landrace × Lantang F2 resource population (n = 257). Association analysis revealed that seven SNPs (except E42) were associated with some of the carcass- and meat quality-related traits. Particularly, significant associations of three SNPs (E53, E82, and E36) with backfat thickness traits were observed. Further, the genetic effects of E53 on four live backfat thickness traits were validated in an independent population (n = 221). More investigations about E53 sequence characteristics were performed, i.e., radiation hybrid (RH) mapping, 3'-RACE, and screening analysis of the positive BAC clones. Our research identified the genetic effects of eight EST-derived SNPs on carcass and meat quality traits, and suggested that E53 may be a useful marker for live backfat thickness traits in pig breeding programs.

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Quantitative Trait Loci Mapping for Porcine Backfat Thickness

Cited by 7 publications

References 27 publications

Genetic Variation and Association of Insulin-Like Growth Factor Binding Protein-3 with Performance in Swine

Genetic Variation and Association of Insulin-Like Growth Factor Binding Protein-3 with Performance in Swine

Mapping Quantitative Trait Loci for Meat Quality on Pig Chromosome 3, 4 and 7

Association of eight EST-derived SNPs with carcass and meat quality traits in pigs

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