Quantitative sensory testing

Siao, Peter; Cros, Didier

doi:10.1016/s1047-9651(02)00122-5

Cited by 105 publications

(88 citation statements)

References 81 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Although the semi-objective methods used in the QST measurements have high method sensitivity and reproducibility in healthy adults, 30,38 session-tosession effects must always be taken into account when interpreting the data. These session-to-session effects are a well-known confounder in semi-objective psychophysical methods such as QST and are due to the fact that subjects get used to the test situation and therefore tend to be more alert at the following session, in turn resulting in modified thresholds and tolerance time over time.…”

Section: Discussionmentioning

confidence: 99%

“…15 Thenar region measurements have been shown to accurately reflect overall pain sensitivity with high method sensitivity and reproducibility. 37,38 To measure the thermal perception threshold, done according to the method of limits, 37 four cold stimuli followed by four warm stimuli (starting at 32 ± 0.5°C; and with stimulus rate of 1°C/s) were given with a randomized inter-stimulus interval of 4-6 s, the latter with the purpose of avoiding habituation by the test subjects. The subject was instructed to press a cut-off button as soon as she/he perceived the sensation of heat or cold, respectively.…”

Section: Equipment and Test Set-upmentioning

confidence: 99%

See 1 more Smart Citation

Influence of Estrogen Levels on Thermal Perception, Pain Thresholds, and Pain Tolerance: Studies on Women Undergoing in Vitro Fertilization

Stening

Berg

Hammar

et al. 2012

The Journal of Pain

View full text Add to dashboard Cite

We examined the relationship between estrogen and pain in women undergoing in vitro fertilization (IVF). Quantitative sensory tests (QST) were performed twice during the IVF-regimen: once during hormonal down-regulation and once during hormonal upregulation. A group of healthy men and a group of women using monophasic contraceptives were also examined, to control for session-to-session effects. Among the women undergoing IVF, serum 17β-estradiol levels differed strongly between treatments as expected, and increased from 65.7 (SD = 26) pmol/l during the downregulation phase, to 5188 (SD = 2524) pmol/l during the up-regulation phase.Significant outcomes in the QST were only seen for temperature perception thresholds (1.7°C vs. 2.2°C; P = 0.003) and cold pain threshold (11.5°C vs. 14.5°C; P = 0.04). A similar change in cold pain threshold was also seen in the two control groups, however, and statistical analysis suggested that this change was due to a session-to-session effect rather than being the result of hormonal modulation. Heat pain thresholds, heat tolerance, pressure pain thresholds, and the cold pressor test showed no significant differences between sessions. These data demonstrate that pain perception and pain thresholds in healthy women show little, if any, changes even with major variations in serum estradiol levels. PerspectiveThis study shows that pain perception and tolerance in women undergoing in vitro fertilization do not vary, despite the dramatic changes in 17β-estradiol levels induced by the treatment regimen. The result thus suggests that in humans, contrary to experimental animals, changes in estrogen levels have little influence on pain sensitivity.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Equipment and Test Set-upmentioning

confidence: 99%

Influence of Estrogen Levels on Thermal Perception, Pain Thresholds, and Pain Tolerance: Studies on Women Undergoing in Vitro Fertilization

Stening

Berg

Hammar

et al. 2012

The Journal of Pain

View full text Add to dashboard Cite

show abstract

“…To assess this loss of sensation early in the course of disease, QST utilises a variety of instruments that deliver specific stimuli at designated intensities, providing a non-invasive parametric gauge of sensory function (i.e. perceptions of light touch or pressure, vibration, heat and cold, and pain) and axonal pathology [19,24].…”

Section: Qst and Vpt Testingmentioning

confidence: 99%

“…Like tactile and thermal perception, vibratory perception reflects specific neuroanatomical pathways with discrete fibre populations [29]. It is neuroselective for large and myelinated A α and A β sensory fibres [24].…”

Section: Qst and Vpt Testingmentioning

confidence: 99%

Vibration perception threshold—a valuable assessment of neural dysfunction in people with diabetes

Garrow¹,

Boulton²

2006

Diabetes Metabolism Res

View full text Add to dashboard Cite

Diabetic peripheral neuropathy (DPN) has been identified as a key element in the causal pathway to foot ulceration and other lower-extremity complications, impaired quality of life and increased mortality. Early detection is essential to optimise effective risk management, including adequate foot care, patient education, and future pharmacological therapy. However, data suggest that screening has been mostly sub-optimal, and many physicians remain unfamiliar with non-invasive screening tests. There is evidence in the literature to suggest that vibration perception threshold (VPT) measures can be used to easily and accurately identify at-risk diabetic patients, including those with early neuropathic deficits. These measures have been used in population-based studies and are associated with an increased risk of severe and expensive outcomes, such as ulcers and amputations. Incorporating VPT testing into clinical practice has the potential to significantly improve the outcomes in patients with DPN, thereby substantially reducing the socio-economic burden of this common and challenging disease.

show abstract

“…QST procedures are psychophysical in nature, and involve application of objective, quantifiable physical stimuli that evoke behavioral (e.g., verbal) responses from the individual being tested. QST has been used for decades in clinical research for cutaneous and mucosal assessment of pain sensitivity 32, 85, 86, 87, 88, 89, 90. It can also be used for patient subgroup classification and prognosis 91.…”

Section: Qst In Orofacial Pain and Dentistrymentioning

confidence: 99%

Applications of sensory and physiological measurement in oral‐facial dental pain

Dabiri

Harper

Kapila

et al. 2018

Special Care in Dentistry

View full text Add to dashboard Cite

Dentists regularly employ a variety of self‐report and sensory techniques to aid in the diagnosis and treatment of tooth‐related disease. Many of these techniques leverage principles borrowed from psychophysics, the quantitative measurement of the relationship between stimuli and evoked sensations, which falls under the larger umbrella of quantitative sensory testing (QST). However, most clinicians fail to meet the bar for what could be considered quantitative sensory testing, and instead focus on qualitative and dichotomous “yes/no” aspects of sensory experience. With our current subjective measurements for pain assessments, diagnosis and treatment of dental pain in young children and individuals (any age) with severe cognitive impairment rely extensively on third‐party observations. Consequently, the limitation of inadequate pain diagnosis can lead to poor pain management. In this review, it discusses mechanisms that underlie acute and chronic dental pain. It details the measurement of somatosensory responses and pulpal blood flow as objective measures of tooth health and pain. It proposes that bridging these varied methodologies will significantly improve diagnosis and treatment of orofacial pain and pathology. It concludes that improving the precision of sensory measurements could yield important improvements in diagnostic challenges in pulpal pathology for noncommunicative and cognitively impaired individuals.

show abstract

Quantitative sensory testing

Cited by 105 publications

References 81 publications

Influence of Estrogen Levels on Thermal Perception, Pain Thresholds, and Pain Tolerance: Studies on Women Undergoing in Vitro Fertilization

Influence of Estrogen Levels on Thermal Perception, Pain Thresholds, and Pain Tolerance: Studies on Women Undergoing in Vitro Fertilization

Vibration perception threshold—a valuable assessment of neural dysfunction in people with diabetes

Applications of sensory and physiological measurement in oral‐facial dental pain

Contact Info

Product

Resources

About