2012
DOI: 10.1016/j.jprot.2012.03.033
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Quantitative proteomic analysis of human osteoblast-like MG-63 cells in response to bioinert implant material titanium and polyetheretherketone

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Cited by 47 publications
(35 citation statements)
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“…All tested specimens revealed an almost identical level of intracellular protein content, which is related to normalizing the data against the DNA content of each test group, thus excluding cell count from influencing the data 30 . By employing isotope labeling of amino acids, over 400 proteins were associated with marked changes in expression influenced by type of implant materials 31 . Findings indicate further possibilities to study biocompatibility of implant materials on a molecular level 32 …”
Section: Discussionmentioning
confidence: 96%
“…All tested specimens revealed an almost identical level of intracellular protein content, which is related to normalizing the data against the DNA content of each test group, thus excluding cell count from influencing the data 30 . By employing isotope labeling of amino acids, over 400 proteins were associated with marked changes in expression influenced by type of implant materials 31 . Findings indicate further possibilities to study biocompatibility of implant materials on a molecular level 32 …”
Section: Discussionmentioning
confidence: 96%
“…Among the different implant materials, poly(etheretherketone) (PEEK) is increasingly used as an alternative to metals, especially for spinal fusion, due to excellent resistance to chemicals and sterilization process, and mechanical properties [59][60][61][62]. Nevertheless, PEEK totally lacks bioactivity (bioinert material) [63,64]. IJD has been used to deposit strontium doped-hydroxyapatite films on the PEEK substrates with the aim of improving its bioactivity [65].…”
Section: Bioactive Coatings and Thin Films By Pedmentioning
confidence: 99%
“…Basal kann das modellierte GerĂŒst der Schleimhaut aufl iegen bzw. die defi nitive Kontur der Suprakonstruktion erhalten, da das Hochleistungspolymer eine sehr gute Weichgewebsreaktion zeigt [9,10]. Beim Einbetten des GerĂŒstes sind fĂŒr das Pressverfahren typische EntlĂŒftungskanĂ€le notwendig, damit es zu einem vollstĂ€ndigen Ausfl ießen des GerĂŒstmaterials kommt.…”
Section: Zahntechnische Herstellungunclassified