Quantitative MR Imaging of the Heart

Peshock, Ronald M.; Willett, Duwayne L; Sayad, Dany; Hundley, W. G.; Chwialkowski, M.P.; Clarke, Geoffrey D.; Parkey, Robert W.

doi:10.1016/s1064-9689(21)00182-3

Cited by 44 publications

(5 citation statements)

References 113 publications

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“…Different invasive and non-invasive imaging modalities for the quantitative and, in part, the qualitative assessment of the left ventricular performance are available, including X-ray angiography, 2D and 3D echocardiography, MR imaging, EBT and gated SPECT (12). Over the last decade, MR imaging has become the gold standard for quantification of left ventricular function and has proved its value for the measurement of the regional left ventricular wall motion (28,33). Therefore, in the present study, MSCT was compared to MR imaging as reference standard for quantification of left ventricular function and assessment of left ventricular wall motion.…”

Section: Discussionmentioning

confidence: 99%

“…A precise quantitative and qualitative assessment of the left ventricular function is important for diagnosis, prognosis and therapy in patients with various cardiac diseases (10,15). Although echocardiography is applied routinely (12), magnetic resonance (MR) imaging has become the gold standard for quantification of the left ventricular function and evaluation of ventricular wall motion (28,33). Initial results of the recently introduced retrospectively ECG-gated multislice spiral computed tomography (MSCT) proved the feasibility of this technique for quantitative assessment of the left ventricular function (13,17).…”

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confidence: 99%

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Quantitative and qualitative assessment of left ventricular volume with ECG-gated multislice spiral CT: value of different image reconstruction algorithms in comparison to MRI

et al. 2003

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confidence: 99%

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confidence: 99%

Quantitative and qualitative assessment of left ventricular volume with ECG-gated multislice spiral CT: value of different image reconstruction algorithms in comparison to MRI

et al. 2003

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“…More recently, echocardiography using highfrequency transducers has proven to be useful in estimating LV mass in mice (4,12). Magnetic resonance imaging (MRI) as a three-dimensional approach, independent of geometric assumptions, has proven in numer-ous previous studies to be an accurate technique to quantify left ventricular (LV) mass and function (14). We have extended previous work on cardiac MRI in small animals to the evaluation of LV mass and function in the mouse.…”

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confidence: 95%

Magnetic resonance imaging accurately estimates LV mass in a transgenic mouse model of cardiac hypertrophy

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Peshock

et al. 1998

American Journal of Physiology-Heart and Circulatory Physiology

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Transgenic mice with a dysfunctional guanylyl cyclase A gene (GCA −/−) are unable to transduce the signals from atrial naturetic peptide and develop hypertension and cardiac hypertrophy. Magnetic resonance imaging (MRI) was performed to assess cardiac hypertrophy in these animals, using wild-type siblings as controls. Anesthetized mice were studied by gated multislice, multiphase cine MRI at 1.5 T. Simpson’s rule was used to estimate left ventricle (LV) mass and volumes from short-axis images. Correlation between LV mass evaluated by MRI and at necropsy was excellent, with LVnecropsy = 1.04 × LVMRI + 4.69 mg ( r 2 = 0.95). By MRI, GCA −/− LV mass was significantly different when compared with isogenic controls [GCA −/−, 226 ± 43 mg ( n = 14) vs. controls, 156 ± 14 mg ( n = 10); P < 0.0001]. LV volumes and ejection fraction in the two groups were not significantly different. MRI provides an accurate means for the noninvasive assessment of murine cardiac phenotype and may be useful in following the effects of genetic modification.

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“…Since magnetic resonance imaging (MRI) was the first non-invasive technique to provide high-resolution three-dimensional functional images of the heart, it is regarded by many as the current standard of reference for left ventricular function (22,31,40,(48)(49)(50). The main advantage of MRI is its excellent temporal resolution without exposing the patient to ionizing radiation.…”

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Quantification of global left ventricular function: comparison of multidetector computed tomography and magnetic resonance imaging. a meta-analysis and review of the current literature

et al. 2006

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Cardiac morbidity and mortality are closely related to cardiac volumes and global left ventricular (LV) function, expressed as left ventricular ejection fraction. Accurate assessment of these parameters is required for the prediction of prognosis in individual patients as well as in entire cohorts. The current standard of reference for left ventricular function is analysis by short-axis magnetic resonance imaging. In recent years, major extensive technological improvements have been achieved in computed tomography. The most marked development has been the introduction of the multidetector CT (MDCT), which has significantly improved temporal and spatial resolutions. In order to assess the current status of MDCT for analysis of LV function, the current available literature on this subject was reviewed. The data presented in this review indicate that the global left ventricular functional parameters measured by contemporary multi-detector row systems combined with adequate reconstruction algorithms and post-processing tools show a narrow diagnostic window and are interchangeable with those obtained by MRI.

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Quantitative MR Imaging of the Heart

Cited by 44 publications

References 113 publications

Quantitative and qualitative assessment of left ventricular volume with ECG-gated multislice spiral CT: value of different image reconstruction algorithms in comparison to MRI

Quantitative and qualitative assessment of left ventricular volume with ECG-gated multislice spiral CT: value of different image reconstruction algorithms in comparison to MRI

Magnetic resonance imaging accurately estimates LV mass in a transgenic mouse model of cardiac hypertrophy

Quantification of global left ventricular function: comparison of multidetector computed tomography and magnetic resonance imaging. a meta-analysis and review of the current literature

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